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Metabolic Checkpoints in Differentiation of Helper T Cells in Tissue Inflammation

Naïve CD4(+) T cell differentiate into effector and regulatory subsets of helper T (Th) cells in various pathophysiological conditions and modulate tissue inflammation in autoimmune diseases. While cytokines play a key role in determining the fate of Th cells differentiation, metabolites, and metabo...

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Detalles Bibliográficos
Autores principales: Roy, Suyasha, Rizvi, Zaigham Abbas, Awasthi, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340303/
https://www.ncbi.nlm.nih.gov/pubmed/30692989
http://dx.doi.org/10.3389/fimmu.2018.03036