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Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens

Expression of the Autoimmune regulator (AIRE) outside of the thymus has long been suggested in both humans and mice, but the cellular source in humans has remained undefined. Here we identify AIRE expression in human tonsils and extensively analyzed these “extra-thymic AIRE expressing cells” (eTACs)...

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Detalles Bibliográficos
Autores principales:	Fergusson, Joannah R., Morgan, Michael D., Bruchard, Melanie, Huitema, Leonie, Heesters, Balthasar A., van Unen, Vincent, van Hamburg, Jan Piet, van der Wel, Nicole N., Picavet, Daisy, Koning, Frits, Tas, Sander W., Anderson, Mark S., Marioni, John C., Holländer, Georg A., Spits, Hergen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340304/ https://www.ncbi.nlm.nih.gov/pubmed/30692988 http://dx.doi.org/10.3389/fimmu.2018.02902

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