Cargando…

Oral cannabinoids in people living with HIV on effective antiretroviral therapy: CTN PT028—study protocol for a pilot randomised trial to assess safety, tolerability and effect on immune activation

INTRODUCTION: Despite antiretroviral therapy (ART), people living with HIV have higher rates of non-infectious chronic diseases. These conditions are driven by relatively high levels of inflammation persisting on ART compared with uninfected individuals. Chronic inflammation also contributes to HIV...

Descripción completa

Detalles Bibliográficos
Autores principales:	Costiniuk, Cecilia T, Saneei, Zahra, Routy, Jean-Pierre, Margolese, Shari, Mandarino, Enrico, Singer, Joel, Lebouché, Bertrand, Cox, Joseph, Szabo, Jason, Brouillette, Marie-Josée, Klein, Marina B, Chomont, Nicolas, Jenabian, Mohammad-Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	HIV/AIDS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340429/ https://www.ncbi.nlm.nih.gov/pubmed/30659041 http://dx.doi.org/10.1136/bmjopen-2018-024793

Ejemplares similares

Effects of Oral Cannabinoids on Systemic Inflammation and Viral Reservoir Markers in People with HIV on Antiretroviral Therapy: Results of the CTN PT028 Pilot Clinical Trial
por: Mboumba Bouassa, Ralph-Sydney, et al.
Publicado: (2023)

CTN 328: immunogenicity outcomes in people living with HIV in Canada following vaccination for COVID-19 (HIV-COV): protocol for an observational cohort study
por: Costiniuk, Cecilia T, et al.
Publicado: (2021)

Camu Camu effects on microbial translocation and systemic immune activation in ART-treated people living with HIV: protocol of the single-arm non-randomised Camu Camu prebiotic pilot study (CIHR/CTN PT032)
por: Isnard, Stéphane, et al.
Publicado: (2022)

Influence of letermovir treatment on gut inflammation in people living with HIV on antiretroviral therapy: protocol of the open-label controlled randomised CIAO study
por: Royston, Léna, et al.
Publicado: (2023)

The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy – CTN PT006: study protocol for a randomized controlled trial
por: Lebouché, Bertrand, et al.
Publicado: (2014)

Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028) †
por: Mboumba Bouassa, Ralph-Sydney, et al.
Publicado: (2022)

Strategies to improve adherence to antiretroviral therapy and retention in care for people living with HIV in high-income countries: a protocol for an overview of systematic reviews
por: Mbuagbaw, Lawrence, et al.
Publicado: (2018)

Overview of systematic reviews on strategies to improve treatment initiation, adherence to antiretroviral therapy and retention in care for people living with HIV: part 1
por: Mbuagbaw, Lawrence, et al.
Publicado: (2020)

Role of fatty liver in the epidemic of advanced chronic liver disease among people with HIV: protocol for the Canadian LIVEHIV multicentre prospective cohort
por: Cinque, Felice, et al.
Publicado: (2023)

Effect of metformin on the size of the HIV reservoir in non-diabetic ART-treated individuals: single-arm non-randomised Lilac pilot study protocol
por: Routy, Jean-Pierre, et al.
Publicado: (2019)

Effects of Recombinant Human Interleukin 7 on T-Cell Recovery and Thymic Output in HIV-Infected Patients Receiving Antiretroviral Therapy: Results of a Phase I/IIa Randomized, Placebo-Controlled, Multicenter Study
por: Lévy, Y., et al.
Publicado: (2012)

Poor Prognosis of HIV-Associated Tuberculous Meningitis Regardless of the Timing of Antiretroviral Therapy
por: Lawn, Stephen D., et al.
Publicado: (2011)

Antiretroviral Choice for HIV Impacts Antimalarial Exposure and Treatment Outcomes in Ugandan Children
por: Parikh, Sunil, et al.
Publicado: (2016)

Cohort profile: The Observational cohort for the study of DOlutegravir in Antiretroviral Combination REgimens (ODOACRE)
por: Ciccullo, Arturo, et al.
Publicado: (2019)

Discontinuation of Intermittent Hemodialysis in HIV-Associated Nephropathy Following Initiation of Antiretroviral Therapy
por: Ghandour, Mohamedanwar, et al.
Publicado: (2021)

Barriers and facilitators associated with steps of the HIV care cascade for migrants in OECD countries: a systematic mixed studies review protocol
por: Arora, Anish, et al.
Publicado: (2020)

Current Scenario of HIV/AIDS, Treatment Options, and Major Challenges with Compliance to Antiretroviral Therapy
por: Bhatti, Adnan Bashir, et al.
Publicado: (2016)

Editorial Commentary: Immunodeficiency at Start of Antiretroviral Therapy: The Persistent Problem of Late Presentation to Care
por: Ford, Nathan, et al.
Publicado: (2015)

Predictors of first-line antiretroviral treatment failure among children on antiretroviral therapy at the University of Gondar comprehensive specialised hospital, North-west, Ethiopia: a 14-year long-term follow-up study
por: Wondifraw, Endalk Birrie, et al.
Publicado: (2022)

Mortality in the Year Following Antiretroviral Therapy Initiation in HIV-Infected Adults and Children in Uganda and Zimbabwe
por: Walker, A. Sarah, et al.
Publicado: (2012)

Impact of Opioid Substitution Therapy on Antiretroviral Therapy Outcomes: A Systematic Review and Meta-Analysis
por: Low, Andrea J., et al.
Publicado: (2016)

Mortality in Hepatitis C Virus–Infected Patients With a Diagnosis of AIDS in the Era of Combination Antiretroviral Therapy
por: Branch, Andrea D., et al.
Publicado: (2012)

RISK FACTORS OF HIV-1 VERTICAL TRANSMISSION (VT) AND THE INFLUENCE OF ANTIRETROVIRAL THERAPY (ART) IN PREGNANCY OUTCOME
por: Barral, Maria F.M., et al.
Publicado: (2014)

ASSOCIATION BETWEEN SMOKING, CRACK COCAINE ABUSE AND THE DISCONTINUATION OF COMBINATION ANTIRETROVIRAL THERAPY IN RECIFE, PERNAMBUCO, BRAZIL
por: Batista, Joanna d'Arc Lyra, et al.
Publicado: (2014)

Retention in care prior to antiretroviral treatment eligibility in sub-Saharan Africa: a systematic review of the literature
por: Plazy, Mélanie, et al.
Publicado: (2015)

Progression of Liver Fibrosis and Modern Combination Antiretroviral Therapy Regimens in HIV-Hepatitis C–Coinfected Persons
por: Brunet, Laurence, et al.
Publicado: (2016)

Antiretroviral Therapy to Prevent HIV Acquisition in Serodiscordant Couples in a Hyperendemic Community in Rural South Africa
por: Oldenburg, Catherine E., et al.
Publicado: (2016)

Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis
por: Siemieniuk, Reed A, et al.
Publicado: (2017)

Pregnancy outcome among HIV-infected women on different antiretroviral therapies in Ethiopia: a cohort study
por: Ejigu, Yohannes, et al.
Publicado: (2019)

Qualitative study of the BREATHER trial (Short Cycle antiretroviral therapy): is it acceptable to young people living with HIV?
por: Bernays, Sarah, et al.
Publicado: (2017)

Differing spectrum of HIV-associated ophthalmic disease among patients starting antiretroviral therapy in India and South Africa
por: Pathai, Sophia, et al.
Publicado: (2011)

Associations of HIV infection with insulin and glucose levels in antiretroviral-naïve Rwandan women: a cross-sectional analysis
por: Dusingize, Jean Claude, et al.
Publicado: (2013)

Antiretroviral therapy is not associated with reduced herpes simplex virus shedding in HIV coinfected adults: an observational cohort study
por: Tan, Darrell H S, et al.
Publicado: (2014)

Establishment and Replenishment of the Viral Reservoir in Perinatally HIV-1-infected Children Initiating Very Early Antiretroviral Therapy
por: Martínez-Bonet, Marta, et al.
Publicado: (2015)

Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy
por: Mukerji, Shibani S., et al.
Publicado: (2016)

Adherence to antiretroviral drug therapy in adult patients who are HIV-positive in Northwest Ethiopia: a study protocol
por: Bezabhe, Woldesellassie M, et al.
Publicado: (2013)

Poor treatment outcomes of children on highly active antiretroviral therapy: protocol for a systematic review and meta-analysis
por: Atalell, Kendalem Asmare, et al.
Publicado: (2020)

Protocol for active safety monitoring of a cohort of patients using a dolutegravir-based antiretroviral regimen in Mozambique
por: Mussá, Merana, et al.
Publicado: (2021)

Incidence and predictors of mortality among adolescents on antiretroviral therapy in Amhara Region, Ethiopia: a retrospective cohort analysis
por: Leshargie, Cheru Tesema, et al.
Publicado: (2022)

Does adherence to antiretroviral therapy differ by place of residence in Nigeria? A systematic review and meta-analysis protocol
por: Badru, Oluwaseun Abdulganiyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j3sc3s8oue706hoin84t6e1ek6