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Study protocol for an open-label, single-arm, multicentre phase II trial to evaluate the efficacy and safety of combined triplet therapy and olanzapine for prevention of carboplatin-induced nausea and vomiting in gynaecological cancer patients
INTRODUCTION: Carboplatin (CBDCA) administered at a dosage of 4 mg/mL/min or more area under the blood concentration-time curve (AUC) is considered to be ranked as the highest chemotherapy-induced nausea and vomiting (CINV) risk of the moderately emetogenic chemotherapy agents. The complete response...
Autores principales: | Iihara, Hirotoshi, Shimokawa, Mototsugu, Abe, Masakazu, Hayasaki, Yoh, Fujita, Yukiyoshi, Nagasawa, Yuki, Sakurai, Michiru, Matsuoka, Rie, Suzuki, Akio, Morishige, Kenichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340435/ https://www.ncbi.nlm.nih.gov/pubmed/30782732 http://dx.doi.org/10.1136/bmjopen-2018-024357 |
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