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Outcome and prognostic factors following palliative craniospinal irradiation for leptomeningeal carcinomatosis
BACKGROUND: Leptomeningeal carcinomatosis (LC) is a severe complication of metastatic tumor spread to the central nervous system. Prognosis is dismal with a median overall survival (OS) of ~10–15 weeks. Treatment options include radiotherapy (RT) to involved sites, systemic chemo- or targeted therap...
Autores principales: | El Shafie, Rami A, Böhm, Karina, Weber, Dorothea, Lang, Kristin, Schlaich, Fabian, Adeberg, Sebastian, Paul, Angela, Haefner, Matthias F, Katayama, Sonja, Sterzing, Florian, Hörner-Rieber, Juliane, Löw, Sarah, Herfarth, Klaus, Debus, Jürgen, Rieken, Stefan, Bernhardt, Denise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340499/ https://www.ncbi.nlm.nih.gov/pubmed/30697071 http://dx.doi.org/10.2147/CMAR.S182154 |
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