Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

Tissue fibrosis is a major cause of mortality that results from the deposition of matrix proteins by an activated mesenchyme. Macrophages accumulate in fibrosis, but the role of specific subgroups in supporting fibrogenesis has not been investigated in vivo. Here we used single-cell RNA sequencing (...

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Detalles Bibliográficos
Autores principales: Aran, Dvir, Looney, Agnieszka P., Liu, Leqian, Wu, Esther, Fong, Valerie, Hsu, Austin, Chak, Suzanna, Naikawadi, Ram P., Wolters, Paul J., Abate, Adam R., Butte, Atul J., Bhattacharya, Mallar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340744/
https://www.ncbi.nlm.nih.gov/pubmed/30643263
http://dx.doi.org/10.1038/s41590-018-0276-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340744/
https://www.ncbi.nlm.nih.gov/pubmed/30643263
http://dx.doi.org/10.1038/s41590-018-0276-y

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