Cargando…
Increased freedom of movement in the nascent chain results in dynamic changes in the structure of the SecM arrest motif
Ribosomes are responsible for the synthesis of all cellular proteins. Due to the diversity of sequence and properties, it was initially believed that translating nascent chains would travel unhindered through the ribosome exit tunnel, however a small but increasing number of proteins have been ident...
Autores principales: | Bracken, Hazel A., Woolhead, Cheryl A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340945/ https://www.ncbi.nlm.nih.gov/pubmed/30563926 http://dx.doi.org/10.1042/BSR20181246 |
Ejemplares similares
-
Nascent SecM Chain Outside the Ribosome Reinforces Translation Arrest
por: Yang, Zhuohao, et al.
Publicado: (2015) -
Nascent SecM chain interacts with outer ribosomal surface to stabilize translation arrest
por: Muta, Mikihisa, et al.
Publicado: (2020) -
Mechanisms of ribosome stalling by SecM at multiple elongation steps
por: Zhang, Jun, et al.
Publicado: (2015) -
SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center
por: Bhushan, Shashi, et al.
Publicado: (2011) -
Charge-driven dynamics of nascent chain movement through the SecYEG translocon
por: Ismail, Nurzian, et al.
Publicado: (2015)