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Behavioral training rescues motor deficits in Cyfip1 haploinsufficiency mouse model of autism spectrum disorders
Deletions in the 15q11.2 region of the human genome are associated with neurobehavioral deficits, and motor development delay, as well as in some cases, symptoms of autism or schizophrenia. The cytoplasmic FMRP-interacting protein 1 (CYFIP1) is one of the four genes contained within this locus and h...
Autores principales: | Bachmann, Sven O., Sledziowska, Monika, Cross, Ellen, Kalbassi, Shireene, Waldron, Sophie, Chen, Fangli, Ranson, Adam, Baudouin, Stéphane J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341103/ https://www.ncbi.nlm.nih.gov/pubmed/30664619 http://dx.doi.org/10.1038/s41398-018-0338-9 |
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