Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands

The molecular pathogenesis of salivary gland acinic cell carcinoma (AciCC) is poorly understood. The secretory Ca-binding phosphoprotein (SCPP) gene cluster at 4q13 encodes structurally related phosphoproteins of which some are specifically expressed at high levels in the salivary glands and constit...

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Detalles Bibliográficos
Autores principales: Haller, Florian, Bieg, Matthias, Will, Rainer, Körner, Cindy, Weichenhan, Dieter, Bott, Alexander, Ishaque, Naveed, Lutsik, Pavlo, Moskalev, Evgeny A., Mueller, Sarina K., Bähr, Marion, Woerner, Angelika, Kaiser, Birgit, Scherl, Claudia, Haderlein, Marlen, Kleinheinz, Kortine, Fietkau, Rainer, Iro, Heinrich, Eils, Roland, Hartmann, Arndt, Plass, Christoph, Wiemann, Stefan, Agaimy, Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341107/
https://www.ncbi.nlm.nih.gov/pubmed/30664630
http://dx.doi.org/10.1038/s41467-018-08069-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341107/
https://www.ncbi.nlm.nih.gov/pubmed/30664630
http://dx.doi.org/10.1038/s41467-018-08069-x

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