Cargando…

Can targeted metabolomics predict depression recovery? Results from the CO-MED trial

Metabolomics is a developing and promising tool for exploring molecular pathways underlying symptoms of depression and predicting depression recovery. The AbsoluteIDQ™ p180 kit was used to investigate whether plasma metabolites (sphingomyelins, lysophosphatidylcholines, phosphatidylcholines, and acy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Czysz, Andrew H., South, Charles, Gadad, Bharathi S., Arning, Erland, Soyombo, Abigail, Bottiglieri, Teodoro, Trivedi, Madhukar H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341111/ https://www.ncbi.nlm.nih.gov/pubmed/30664617 http://dx.doi.org/10.1038/s41398-018-0349-6

Ejemplares similares

Fibroblast growth factor 21 (FGF21) is increased in MDD and interacts with body mass index (BMI) to affect depression trajectory
por: Mason, Brittany L., et al.
Publicado: (2022)

Higher S100B Levels Predict Persistently Elevated Anhedonia with Escitalopram Monotherapy Versus Antidepressant Combinations: Findings from CO-MED Trial
por: Jha, Manish K., et al.
Publicado: (2019)

Metabolomic Profiling of Adults with Congenital Heart Disease
por: Cedars, Ari, et al.
Publicado: (2021)

Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy
por: Tondo, Mireia, et al.
Publicado: (2020)

Platelet-Derived Growth Factor as an Antidepressant Treatment Selection Biomarker: Higher Levels Selectively Predict Better Outcomes with Bupropion-SSRI Combination
por: Jha, Manish K, et al.
Publicado: (2017)

Absorption and Tissue Distribution of Folate Forms in Rats: Indications for Specific Folate Form Supplementation during Pregnancy
por: Bobrowski-Khoury, Natasha, et al.
Publicado: (2022)

Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice
por: Sontag, Jean-Marie, et al.
Publicado: (2014)

Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia
por: Dayal, Sanjana, et al.
Publicado: (2017)

Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore
por: Inoue-Choi, Maki, et al.
Publicado: (2013)

Brain–blood amino acid correlates following protein restriction in murine maple syrup urine disease
por: Vogel, Kara R, et al.
Publicado: (2014)

Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice
por: Belik, Jaques, et al.
Publicado: (2017)

Corrigendum: Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice
por: Belik, Jaques, et al.
Publicado: (2017)

Physiological competition of brain phenylalanine accretion: Initial pharmacokinetic analyses of aminoisobutyric and methylaminoisobutyric acids in Pah(enu2 −/−) mice
por: Vogel, Kara R., et al.
Publicado: (2015)

Prediction of Acute-Phase Treatment Outcomes by Adding a Single-Item Measure of Activity Impairment to Symptom Measurement: Development and Validation of an Interactive Calculator from the STAR*D and CO-MED Trials
por: Jha, Manish K, et al.
Publicado: (2019)

Impact of the COVID-19 pandemic on adults with current and prior depression: initial findings from the longitudinal Texas RAD study
por: Czysz, Andrew H., et al.
Publicado: (2021)

Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase‐deficient mice
por: Brown, Madalyn N., et al.
Publicado: (2020)

Revisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine
por: Lerin, Carles, et al.
Publicado: (2023)

Targeted metabolomic analysis in Parkinson’s disease brain frontal cortex and putamen with relation to cognitive impairment
por: Kalecký, Karel, et al.
Publicado: (2023)

Relationship of Cerebrospinal Fluid Vitamin B12 Status Markers With Parkinson's Disease Progression
por: Christine, Chadwick W., et al.
Publicado: (2020)

[6S]-5-Methyltetrahydrofolic Acid and Folic Acid Pregnancy Diets Differentially Program Metabolic Phenotype and Hypothalamic Gene Expression of Wistar Rat Dams Post-Birth
por: Pannia, Emanuela, et al.
Publicado: (2020)

Protective Vascular and Cardiac Effects of Inducible Nitric Oxide Synthase in Mice with Hyperhomocysteinemia
por: Dayal, Sanjana, et al.
Publicado: (2014)

Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia
por: Gu, Sean X., et al.
Publicado: (2020)

Dysregulated DNA methylation in the pathogenesis of Fabry disease
por: Shen, Jin-Song, et al.
Publicado: (2022)

Targeted Metabolomic Analysis in Alzheimer’s Disease Plasma and Brain Tissue in Non-Hispanic Whites
por: Kalecký, Karel, et al.
Publicado: (2022)

Rett syndrome (MECP2) and succinic semialdehyde dehydrogenase (ALDH5A1) deficiency in a developmentally delayed female
por: Brown, Madalyn, et al.
Publicado: (2019)

Hyperhomocysteinemia Potentiates Hyperglycemia-Induced Inflammatory Monocyte Differentiation and Atherosclerosis
por: Fang, Pu, et al.
Publicado: (2014)

One-carbon metabolism in children with marasmus and kwashiorkor
por: May, Thaddaeus, et al.
Publicado: (2022)

Biomarkers and the Future of Treatment for Depression
por: Toups, Marisa, et al.
Publicado: (2012)

Novel biomarkers and age-related metabolite correlations in plasma and dried blood spots from patients with succinic semialdehyde dehydrogenase deficiency
por: Kirby, Trevor, et al.
Publicado: (2020)

SaudiMEDs and CanMEDs frameworks: similarities and differences
por: Shadid, Asem M, et al.
Publicado: (2019)

Addressing adherence to antidepressant treatment for depression
por: Mayes, Taryn L., et al.
Publicado: (2020)

Clinically Significant Changes in the 17- and 6-Item Hamilton Rating Scales for Depression: A STAR*D Report
por: Rush, Augustus John, et al.
Publicado: (2021)

Watering CanMEDS flowers
por: Voll, Sarah, et al.
Publicado: (2017)

Treatment strategies to improve and sustain remission in major depressive disorder
por: Madhukar H., Trivedi, et al.
Publicado: (2008)

A review of quetiapine in combination with antidepressant therapy in patients with depression
por: Daly, Ella J, et al.
Publicado: (2007)

Worsening Anxiety, Irritability, Insomnia, or Panic Predicts Poorer Antidepressant Treatment Outcomes: Clinical Utility and Validation of the Concise Associated Symptom Tracking (CAST) Scale
por: Jha, Manish K, et al.
Publicado: (2017)

Virtual Care in CanMEDS 2025
por: Stovel, Rebecca G, et al.
Publicado: (2023)

Anti-racism in CanMEDS 2025
por: Osei-Tutu, Kannin, et al.
Publicado: (2023)

Clinical Reasoning in CanMEDS 2025
por: Young, Meredith, et al.
Publicado: (2023)

Physician Humanism in CanMEDS 2025
por: Waters, Heather M, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cv1picne4c7ba0lhug7gj7l40f