Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration

Choroidal neovascularization (CNV) is a major cause of visual impairment in patients suffering from wet age-related macular degeneration (AMD), particularly when refractory to intraocular anti-VEGF injections. Here we report that treatment with the oral mineralocorticoid receptor (MR) antagonist spi...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Mantel, Irmela, Gelize, Emmanuelle, Li, Xinxin, Xie, Xiaoyue, Arboleda, Alejandro, Seminel, Marie, Levy-Boukris, Rinath, Dernigoghossian, Marilyn, Prunotto, Andrea, Andrieu-Soler, Charlotte, Rivolta, Carlo, Canonica, Jérémie, Naud, Marie-Christine, Lechner, Sebastian, Farman, Nicolette, Bravo-Osuna, Irene, Herrero-Vanrell, Rocio, Jaisser, Frederic, Behar-Cohen, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341116/
https://www.ncbi.nlm.nih.gov/pubmed/30664640
http://dx.doi.org/10.1038/s41467-018-08125-6

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