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Synaptotagmin Ca(2+) Sensors and Their Spatial Coupling to Presynaptic Ca(v) Channels in Central Cortical Synapses
Ca(2+) concentrations drop rapidly over a distance of a few tens of nanometers from an open voltage-gated Ca(2+) channel (Ca(v)), thereby, generating a spatially steep and temporally short-lived Ca(2+) gradient that triggers exocytosis of a neurotransmitter filled synaptic vesicle. These non-steady...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341215/ https://www.ncbi.nlm.nih.gov/pubmed/30697148 http://dx.doi.org/10.3389/fnmol.2018.00494 |