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Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine
Pancreatic acinar cells require high rates of amino acid uptake for digestive enzyme synthesis, but excessive concentrations can trigger acute pancreatitis (AP) by mechanisms that are not well understood. We have used three basic natural amino acids L-arginine, L-ornithine, and L-histidine to determ...
Autores principales: | Zhang, Xiaoying, Jin, Tao, Shi, Na, Yao, Linbo, Yang, Xinmin, Han, Chenxia, Wen, Li, Du, Dan, Szatmary, Peter, Mukherjee, Rajarshi, Liu, Tingting, Xia, Qing, Criddle, David N., Huang, Wei, Chvanov, Michael, Sutton, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341295/ https://www.ncbi.nlm.nih.gov/pubmed/30697165 http://dx.doi.org/10.3389/fphys.2018.01922 |
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