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Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

Pancreatic acinar cells require high rates of amino acid uptake for digestive enzyme synthesis, but excessive concentrations can trigger acute pancreatitis (AP) by mechanisms that are not well understood. We have used three basic natural amino acids L-arginine, L-ornithine, and L-histidine to determ...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoying, Jin, Tao, Shi, Na, Yao, Linbo, Yang, Xinmin, Han, Chenxia, Wen, Li, Du, Dan, Szatmary, Peter, Mukherjee, Rajarshi, Liu, Tingting, Xia, Qing, Criddle, David N., Huang, Wei, Chvanov, Michael, Sutton, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341295/
https://www.ncbi.nlm.nih.gov/pubmed/30697165
http://dx.doi.org/10.3389/fphys.2018.01922

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