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Pure Autonomic Failure with Asymptomatic Hypertensive Urgency: A Case Report and Literature Review

We report the case study of a 70-year-old gentleman who presented with isolated, slowly progressive dizziness after prolonged standing and was eventually diagnosed with pure autonomic failure. Initially, his symptoms improved with the use of midodrine and fludrocortisone, but gradually became refrac...

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Detalles Bibliográficos
Autores principales: Aljohar, Alwaleed, Muayqil, Taim, Aldeeri, Abdulrahman, Jammah, Anwar, Hersi, Ahmad, Alhabib, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341310/
https://www.ncbi.nlm.nih.gov/pubmed/30687067
http://dx.doi.org/10.1159/000495605
Descripción
Sumario:We report the case study of a 70-year-old gentleman who presented with isolated, slowly progressive dizziness after prolonged standing and was eventually diagnosed with pure autonomic failure. Initially, his symptoms improved with the use of midodrine and fludrocortisone, but gradually became refractory and disabling. Despite multiple therapeutic interventions, his symptoms persisted along with worsening supine hypertension. We discuss the challenges faced in the treatment of an uncommon condition and discuss the clinical utility of performing serial 24-h ambulatory monitoring to detect subclinical blood pressure fluctuations.