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Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia

Thrombocytopenia is a frequent complication of cancer may be due to a variety of causes including malignancy itself, acute disease processes, or cancer therapy. Systemic cancer therapy is the most common cause of thrombocytopenia in cancer patients observed nearly two-thirds of patients with solid t...

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Detalles Bibliográficos
Autores principales: Pan, Elizabeth, Hsieh, Eric, Piatek, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341312/
https://www.ncbi.nlm.nih.gov/pubmed/30687065
http://dx.doi.org/10.1159/000495032
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author Pan, Elizabeth
Hsieh, Eric
Piatek, Caroline
author_facet Pan, Elizabeth
Hsieh, Eric
Piatek, Caroline
author_sort Pan, Elizabeth
collection PubMed
description Thrombocytopenia is a frequent complication of cancer may be due to a variety of causes including malignancy itself, acute disease processes, or cancer therapy. Systemic cancer therapy is the most common cause of thrombocytopenia in cancer patients observed nearly two-thirds of patients with solid tumors. Thrombocytopenia with traditional chemotherapy agents is most frequently the result of megakaryocyte cytotoxicity. Oxaliplatin is a platinum derivative commonly used in gastrointestinal malignancies and is associated with drug-induced immune thrombocytopenia.
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spelling pubmed-63413122019-01-25 Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia Pan, Elizabeth Hsieh, Eric Piatek, Caroline Case Rep Oncol Case Report Thrombocytopenia is a frequent complication of cancer may be due to a variety of causes including malignancy itself, acute disease processes, or cancer therapy. Systemic cancer therapy is the most common cause of thrombocytopenia in cancer patients observed nearly two-thirds of patients with solid tumors. Thrombocytopenia with traditional chemotherapy agents is most frequently the result of megakaryocyte cytotoxicity. Oxaliplatin is a platinum derivative commonly used in gastrointestinal malignancies and is associated with drug-induced immune thrombocytopenia. S. Karger AG 2018-12-20 /pmc/articles/PMC6341312/ /pubmed/30687065 http://dx.doi.org/10.1159/000495032 Text en Copyright © 2018 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Pan, Elizabeth
Hsieh, Eric
Piatek, Caroline
Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
title Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
title_full Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
title_fullStr Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
title_full_unstemmed Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
title_short Case Report: Oxaliplatin-Induced Immune-Mediated Thrombocytopenia
title_sort case report: oxaliplatin-induced immune-mediated thrombocytopenia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341312/
https://www.ncbi.nlm.nih.gov/pubmed/30687065
http://dx.doi.org/10.1159/000495032
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