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Protein arginine methyltransferase 5 promotes bladder cancer growth through inhibiting NF-kB dependent apoptosis

Protein arginine methyltransferase 5 (PRMT5) has emerged as a key regulator of tumorigenesis. However, how PRMT5 functions in bladder cancer, the most common malignancy of the urological system, is unknown. We described here that PRMT5 is highly expressed in bladder cancer cell lines and primary hum...

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Detalles Bibliográficos
Autores principales: Hu, Guodong, Wang, Xiu, Han, Yi, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341427/
https://www.ncbi.nlm.nih.gov/pubmed/30713476
http://dx.doi.org/10.17179/excli2018-1719