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Elevated expression of Gab1 promotes breast cancer metastasis by dissociating the PAR complex
BACKGROUND: Breast cancer (BCa) remains as the second leading cause of cancer-related death in women worldwide. The majority of the deaths are due to its progression to metastatic BCa. Although Grb2-associated binding protein 1 (Gab1) has been implicated in tumor proliferation and metastasis in mult...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341703/ https://www.ncbi.nlm.nih.gov/pubmed/30665442 http://dx.doi.org/10.1186/s13046-019-1025-2 |