Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018

We describe a multidrug-resistant Neisseria gonorrhoeae urethritis case with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 belongs to the internationally spreading multidrug-resistan...

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Autores principales: Golparian, Daniel, Rose, Lisa, Lynam, Almida, Mohamed, Aia, Bercot, Beatrice, Ohnishi, Makoto, Crowley, Brendan, Unemo, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341943/
https://www.ncbi.nlm.nih.gov/pubmed/30482267
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.47.1800617
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author Golparian, Daniel
Rose, Lisa
Lynam, Almida
Mohamed, Aia
Bercot, Beatrice
Ohnishi, Makoto
Crowley, Brendan
Unemo, Magnus
author_facet Golparian, Daniel
Rose, Lisa
Lynam, Almida
Mohamed, Aia
Bercot, Beatrice
Ohnishi, Makoto
Crowley, Brendan
Unemo, Magnus
author_sort Golparian, Daniel
collection PubMed
description We describe a multidrug-resistant Neisseria gonorrhoeae urethritis case with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 belongs to the internationally spreading multidrug-resistant ceftriaxone-resistant FC428 clade, initially described in Japan in 2015. IR72 was assigned MSLT ST1903, NG-MAST ST17842 and NG-STAR type 1133, including the ceftriaxone resistance-mediating penA-60.001. Global awareness of spreading ceftriaxone-resistant gonococcal strains that threaten recommended dual therapies is essential.
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spelling pubmed-63419432019-02-11 Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018 Golparian, Daniel Rose, Lisa Lynam, Almida Mohamed, Aia Bercot, Beatrice Ohnishi, Makoto Crowley, Brendan Unemo, Magnus Euro Surveill Rapid Communication We describe a multidrug-resistant Neisseria gonorrhoeae urethritis case with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Ireland, August 2018. Whole-genome sequencing showed that the isolate IR72 belongs to the internationally spreading multidrug-resistant ceftriaxone-resistant FC428 clade, initially described in Japan in 2015. IR72 was assigned MSLT ST1903, NG-MAST ST17842 and NG-STAR type 1133, including the ceftriaxone resistance-mediating penA-60.001. Global awareness of spreading ceftriaxone-resistant gonococcal strains that threaten recommended dual therapies is essential. European Centre for Disease Prevention and Control (ECDC) 2018-11-22 /pmc/articles/PMC6341943/ /pubmed/30482267 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.47.1800617 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Golparian, Daniel
Rose, Lisa
Lynam, Almida
Mohamed, Aia
Bercot, Beatrice
Ohnishi, Makoto
Crowley, Brendan
Unemo, Magnus
Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
title Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
title_full Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
title_fullStr Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
title_full_unstemmed Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
title_short Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018
title_sort multidrug-resistant neisseria gonorrhoeae isolate, belonging to the internationally spreading japanese fc428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, ireland, august 2018
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341943/
https://www.ncbi.nlm.nih.gov/pubmed/30482267
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.47.1800617
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