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Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery?

For oesophageal cancer patients with potentially curative disease, treatment usually comprises neoadjuvant chemoradiotherapy followed by surgery. Several methods are currently used for nutritional support while patients are undergoing neoadjuvant treatment but these do not relieve dysphagia. Stentin...

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Detalles Bibliográficos
Autores principales: Tham, Jennifer E, Tharian, Benjamin, Allen, Patrick B, Spence, Gary, Tham, Tony C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Ulster Medical Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342033/
https://www.ncbi.nlm.nih.gov/pubmed/30675071
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author Tham, Jennifer E
Tharian, Benjamin
Allen, Patrick B
Spence, Gary
Tham, Tony C
author_facet Tham, Jennifer E
Tharian, Benjamin
Allen, Patrick B
Spence, Gary
Tham, Tony C
author_sort Tham, Jennifer E
collection PubMed
description For oesophageal cancer patients with potentially curative disease, treatment usually comprises neoadjuvant chemoradiotherapy followed by surgery. Several methods are currently used for nutritional support while patients are undergoing neoadjuvant treatment but these do not relieve dysphagia. Stenting as a bridge to curative surgery has been explored in several case series and a case control study. This is a review of the current literature on the topic. Some small series have shown it to be safe and effective in relieving dysphagia and malnutrition without adverse effect on surgical outcomes, perioperative complications or delay in surgical resection post neoadjuvant therapy. However, there are sufficient concerns about its adverse impact on oncological outcomes such as a reduction in the R0 resection rates, median time to recurrence and 2 - 3 year overall survival, to not currently recommend its routine use in resectable cancers.
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spelling pubmed-63420332019-01-23 Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery? Tham, Jennifer E Tharian, Benjamin Allen, Patrick B Spence, Gary Tham, Tony C Ulster Med J Grand Rounds For oesophageal cancer patients with potentially curative disease, treatment usually comprises neoadjuvant chemoradiotherapy followed by surgery. Several methods are currently used for nutritional support while patients are undergoing neoadjuvant treatment but these do not relieve dysphagia. Stenting as a bridge to curative surgery has been explored in several case series and a case control study. This is a review of the current literature on the topic. Some small series have shown it to be safe and effective in relieving dysphagia and malnutrition without adverse effect on surgical outcomes, perioperative complications or delay in surgical resection post neoadjuvant therapy. However, there are sufficient concerns about its adverse impact on oncological outcomes such as a reduction in the R0 resection rates, median time to recurrence and 2 - 3 year overall survival, to not currently recommend its routine use in resectable cancers. The Ulster Medical Society 2019-01-22 2019-01 /pmc/articles/PMC6342033/ /pubmed/30675071 Text en Copyright © 2019 Ulster Medical Society http://creativecommons.org/licenses/by-nc-sa/4.0/ The Ulster Medical Society grants to all users on the basis of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Licence the right to alter or build upon the work non-commercially, as long as the author is credited and the new creation is licensed under identical terms.
spellingShingle Grand Rounds
Tham, Jennifer E
Tharian, Benjamin
Allen, Patrick B
Spence, Gary
Tham, Tony C
Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery?
title Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery?
title_full Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery?
title_fullStr Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery?
title_full_unstemmed Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery?
title_short Oesophageal Stents for Potentially Curable Oesophageal Cancer – A Bridge to Surgery?
title_sort oesophageal stents for potentially curable oesophageal cancer – a bridge to surgery?
topic Grand Rounds
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342033/
https://www.ncbi.nlm.nih.gov/pubmed/30675071
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