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Development of dual delivery antituberculotic system containing rifapentine microspheres and adipose stem cells seeded in hydroxyapatite/tricalcium phosphate
BACKGROUND: Low drug concentration in the tuberculosis (TB) lesion and bone defects or nonunion after debridement are two major problems that occur in the course of treating osteo-articular TB. Thus, the combination of drug-delivery system and bone tissue repair appears to be the most promising opti...
Autores principales: | Liang, Qiuzhen, Song, Xinghua, She, Shengli, Wang, Zhen, Wang, Chong, Jiang, Dawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342215/ https://www.ncbi.nlm.nih.gov/pubmed/30705585 http://dx.doi.org/10.2147/DDDT.S190696 |
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