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Screening of novel HSP-inducing compounds to conserve cardiomyocyte function in experimental atrial fibrillation

BACKGROUND: The heat shock protein (HSP) inducer, geranylgeranylacetone (GGA), was previously found to protect against atrial fibrillation (AF) remodeling in experimental model systems. Clinical application of GGA in AF is limited, due to low systemic concentrations owing to the hydrophobic characte...

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Detalles Bibliográficos
Autores principales:	van Marion, Denise MS, Hu, Xu, Zhang, Deli, Hoogstra-Berends, Femke, Seerden, Jean-Paul G, Loen, Lizette, Heeres, Andre, Steen, Herman, Henning, Robert H, Brundel, Bianca JJM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342224/ https://www.ncbi.nlm.nih.gov/pubmed/30705583 http://dx.doi.org/10.2147/DDDT.S176924

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