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Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department
OBJECTIVE: To achieve an optimal effect in patients with sepsis at the emergency department (ED), the gentamicin peak-concentration should be sufficiently high (i.e. peak-concentration/MIC ≥8–10). ICU patients with sepsis often need higher gentamicin doses to achieve sufficiently high peak-concentra...
Autores principales: | Cobussen, Maarten, Stassen, Patricia M., Posthouwer, Dirk, van Tiel, Frank H., Savelkoul, Paul H. M., Havenith, Thomas, Haeseker, Michiel B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342306/ https://www.ncbi.nlm.nih.gov/pubmed/30668571 http://dx.doi.org/10.1371/journal.pone.0210012 |
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