Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats

We determined if HIV-1 expression in transgenic (HIV-1-Tg) rats enhanced hepatic genomic changes related to oxidative/nitrosative stress and lipogenesis during cART-treatment, and assessed effects of Mg-supplementation. A clinically used cART (atazanavir-ritonavir+Truvada) was given orally to contro...

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Detalles Bibliográficos
Autores principales: ElZohary, Lama, Weglicki, William B., Chmielinska, Joanna J., Kramer, Jay H., Mak, I. Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342322/
https://www.ncbi.nlm.nih.gov/pubmed/30668566
http://dx.doi.org/10.1371/journal.pone.0210107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342322/
https://www.ncbi.nlm.nih.gov/pubmed/30668566
http://dx.doi.org/10.1371/journal.pone.0210107

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