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Recruitment of Vps34 PI3K and enrichment of PI3P phosphoinositide in the viral replication compartment is crucial for replication of a positive-strand RNA virus

Tombusviruses depend on subversions of multiple host factors and retarget cellular pathways to support viral replication. In this work, we demonstrate that tomato bushy stunt virus (TBSV) and the closely-related carnation Italian ringspot virus (CIRV) recruit the cellular Vps34 phosphatidylinositol...

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Detalles Bibliográficos
Autores principales:	Feng, Zhike, Xu, Kai, Kovalev, Nikolay, Nagy, Peter D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342326/ https://www.ncbi.nlm.nih.gov/pubmed/30625229 http://dx.doi.org/10.1371/journal.ppat.1007530

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