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Keep moving and stay in a good shape to find your homologous recombination partner

Genomic DNA is constantly exposed to damage. Among the lesion in DNA, double-strand breaks (DSB), because they disrupt the two strands of the DNA double helix, are the more dangerous. DSB are repaired through two evolutionary conserved mechanisms: Non-Homologous End Joining (NHEJ) and Homologous Rec...

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Detalles Bibliográficos
Autores principales: Bordelet, Hélène, Dubrana, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342867/
https://www.ncbi.nlm.nih.gov/pubmed/30097675
http://dx.doi.org/10.1007/s00294-018-0873-1