(Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations

BACKGROUND: Although constitutive activating mutations in the Wnt/β-catenin signalling pathway are important for colorectal cancer development, canonical signalling through Wnt ligands is essential for β-catenin activation. Here, we investigated the role of (pro)renin receptor ((P)RR), a component o...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Juan, Shibayama, Yuki, Zhang, Anqi, Ohsaki, Hiroyuki, Asano, Eisuke, Suzuki, Yasuyuki, Kushida, Yoshio, Kobara, Hideki, Masaki, Tsutomu, Wang, Zhiyu, Nishiyama, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342928/
https://www.ncbi.nlm.nih.gov/pubmed/30555158
http://dx.doi.org/10.1038/s41416-018-0350-0

Ejemplares similares

Ejemplares similares