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A promoter variant in ZNF804A decreasing its expression increases the risk of autism spectrum disorder in the Han Chinese population

Synaptic pathology may be one of the cellular substrates underlying autism spectrum disorder (ASD). ZNF804A is a transcription factor that can affect or regulate the expression of many candidate genes involved in ASD. It also localizes at synapses and regulates neuronal and synaptic morphology. So f...

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Detalles Bibliográficos
Autores principales: Zhang, Linna, Qin, Yue, Gong, Xiaohong, Peng, Rui, Cai, Chunquan, Zheng, Yufang, Du, Yasong, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342935/
https://www.ncbi.nlm.nih.gov/pubmed/30670685
http://dx.doi.org/10.1038/s41398-019-0369-x

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