Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors

Immune checkpoint inhibitors have shown unprecedented clinical activity in a variety of cancer types, but only in a fraction of patients. Promising in vivo synergies have been demonstrated between checkpoint inhibitors and other drugs and/or chemotherapy or radiotherapy, and effective models are now...

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Detalles Bibliográficos
Autor principal: Bertolini, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342965/
https://www.ncbi.nlm.nih.gov/pubmed/30538261
http://dx.doi.org/10.1038/s41416-018-0353-x
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author Bertolini, Francesco
author_facet Bertolini, Francesco
author_sort Bertolini, Francesco
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description Immune checkpoint inhibitors have shown unprecedented clinical activity in a variety of cancer types, but only in a fraction of patients. Promising in vivo synergies have been demonstrated between checkpoint inhibitors and other drugs and/or chemotherapy or radiotherapy, and effective models are now needed to select the best combinatorial regimen and disease setting.
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spelling pubmed-63429652019-12-11 Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors Bertolini, Francesco Br J Cancer Editorial Immune checkpoint inhibitors have shown unprecedented clinical activity in a variety of cancer types, but only in a fraction of patients. Promising in vivo synergies have been demonstrated between checkpoint inhibitors and other drugs and/or chemotherapy or radiotherapy, and effective models are now needed to select the best combinatorial regimen and disease setting. Nature Publishing Group UK 2018-12-11 2019-01-22 /pmc/articles/PMC6342965/ /pubmed/30538261 http://dx.doi.org/10.1038/s41416-018-0353-x Text en © Cancer Research UK 2018 https://creativecommons.org/licenses/by/4.0/This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution 4.0 International (CC BY 4.0)
spellingShingle Editorial
Bertolini, Francesco
Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors
title Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors
title_full Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors
title_fullStr Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors
title_full_unstemmed Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors
title_short Desperately seeking…Models to find the right partner and the best use for checkpoint inhibitors
title_sort desperately seeking…models to find the right partner and the best use for checkpoint inhibitors
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342965/
https://www.ncbi.nlm.nih.gov/pubmed/30538261
http://dx.doi.org/10.1038/s41416-018-0353-x
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