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Breast Cancer Diagnosis: Cascade Reaction in Human Live Tissue Allows Clinically Applicable Diagnosis of Breast Cancer Morphology (Adv. Sci. 2/2019)

In article number 1801479, Shinzaburo Noguchi, Katsunori Tanaka, and co‐workers use a click‐to‐sense probe to detect acrolein, which is universally produced by cancer cells under oxidative stress, within five minutes at room temperature. All cancer types tested are imaged and discriminated through m...

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Detalles Bibliográficos
Autores principales: Tanei, Tomonori, Pradipta, Ambara R., Morimoto, Koji, Fujii, Motoko, Arata, Mayumi, Ito, Akihiro, Yoshida, Minoru, Saigitbatalova, Elena, Kurbangalieva, Almira, Ikeda, Jun‐ichiro, Morii, Eiichi, Noguchi, Shinzaburo, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343059/
http://dx.doi.org/10.1002/advs.201970008
Descripción
Sumario:In article number 1801479, Shinzaburo Noguchi, Katsunori Tanaka, and co‐workers use a click‐to‐sense probe to detect acrolein, which is universally produced by cancer cells under oxidative stress, within five minutes at room temperature. All cancer types tested are imaged and discriminated through multiple cascade reactions in the living tissue of human patients. This probe can be used to quickly and accurately diagnose cancer morphology during breast‐conserving surgery, by reforming the conventional pathological methods. [Image: see text]