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Less Is More: Toward a Genome-Reduced Bacillus Cell Factory for “Difficult Proteins”
[Image: see text] The availability of complete genome sequences and the definition of essential gene sets were fundamental in the start of the genome engineering era. In a recent study, redundant and unnecessary genes were systematically deleted from the Gram-positive bacterium Bacillus subtilis, an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343112/ https://www.ncbi.nlm.nih.gov/pubmed/30540431 http://dx.doi.org/10.1021/acssynbio.8b00342 |