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Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis

INTRODUCTION: Moraxella catarrhalis are part of the normal flora of the human respiratory tract and are known to have low pathogenic potential. The organism is rarely reported in the literature as the causative agent of meningitis. We report the first case of early-onset neonatal meningitis associat...

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Autores principales: Siwakoti, Shraddha, Bajracharya, Sohani, Adhikaree, Neetu, Sah, Rinku, Rajbhandari, Rupa Singh, Khanal, Basudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343129/
https://www.ncbi.nlm.nih.gov/pubmed/30729056
http://dx.doi.org/10.1155/2019/4740504
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author Siwakoti, Shraddha
Bajracharya, Sohani
Adhikaree, Neetu
Sah, Rinku
Rajbhandari, Rupa Singh
Khanal, Basudha
author_facet Siwakoti, Shraddha
Bajracharya, Sohani
Adhikaree, Neetu
Sah, Rinku
Rajbhandari, Rupa Singh
Khanal, Basudha
author_sort Siwakoti, Shraddha
collection PubMed
description INTRODUCTION: Moraxella catarrhalis are part of the normal flora of the human respiratory tract and are known to have low pathogenic potential. The organism is rarely reported in the literature as the causative agent of meningitis. We report the first case of early-onset neonatal meningitis associated with M. catarrhalis from Nepal. CASE REPORT: A 3-day-old baby with fever and yellowish discolouration of the body since 48 hrs was admitted to the neonatal ward. The baby developed 3 episodes of seizures in the form of uprolling of eyes on the first day of admission during phototherapy course for raised serum bilirubin. Sepsis screen was positive, and meningitis was confirmed as the cerebrospinal fluid culture grew M. catarrhalis. Cranial ultrasound scan was normal. The baby received a 21-day course of intravenous cefotaxime and amikacin. Recovery has been uneventful to date. CONCLUSION: Neonatal meningitis is a life-threatening infection. This case report presents an uncommon aetiology of neonatal meningitis which can be misidentified in the diagnostic bacteriology laboratory in resource constraints area like ours.
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spelling pubmed-63431292019-02-06 Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis Siwakoti, Shraddha Bajracharya, Sohani Adhikaree, Neetu Sah, Rinku Rajbhandari, Rupa Singh Khanal, Basudha Case Rep Pediatr Case Report INTRODUCTION: Moraxella catarrhalis are part of the normal flora of the human respiratory tract and are known to have low pathogenic potential. The organism is rarely reported in the literature as the causative agent of meningitis. We report the first case of early-onset neonatal meningitis associated with M. catarrhalis from Nepal. CASE REPORT: A 3-day-old baby with fever and yellowish discolouration of the body since 48 hrs was admitted to the neonatal ward. The baby developed 3 episodes of seizures in the form of uprolling of eyes on the first day of admission during phototherapy course for raised serum bilirubin. Sepsis screen was positive, and meningitis was confirmed as the cerebrospinal fluid culture grew M. catarrhalis. Cranial ultrasound scan was normal. The baby received a 21-day course of intravenous cefotaxime and amikacin. Recovery has been uneventful to date. CONCLUSION: Neonatal meningitis is a life-threatening infection. This case report presents an uncommon aetiology of neonatal meningitis which can be misidentified in the diagnostic bacteriology laboratory in resource constraints area like ours. Hindawi 2019-01-09 /pmc/articles/PMC6343129/ /pubmed/30729056 http://dx.doi.org/10.1155/2019/4740504 Text en Copyright © 2019 Shraddha Siwakoti et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Siwakoti, Shraddha
Bajracharya, Sohani
Adhikaree, Neetu
Sah, Rinku
Rajbhandari, Rupa Singh
Khanal, Basudha
Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis
title Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis
title_full Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis
title_fullStr Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis
title_full_unstemmed Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis
title_short Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen‐Moraxella catarrhalis
title_sort early-onset neonatal meningitis caused by an unusual pathogen‐moraxella catarrhalis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343129/
https://www.ncbi.nlm.nih.gov/pubmed/30729056
http://dx.doi.org/10.1155/2019/4740504
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