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High Glucose with Insulin Induces Cell Cycle Progression and Activation of Oncogenic Signaling of Bladder Epithelial Cells Cotreated with Metformin and Pioglitazone
Metformin and pioglitazone are two commonly prescribed oral hypoglycemic agents for diabetes. Recent evidence suggests that these drugs may contribute to bladder cancer. This study investigated molecular mechanism underlying effects of metformin and pioglitazone in bladder epithelial carcinogenesis...
Autores principales: | Kim, Daejin, Ahn, Byul-Nim, Kim, YeongSeok, Hur, Dae Young, Yang, Jae Wook, Park, Ga Bin, Jang, Jung Eun, Lee, Eun Ju, Kwon, Min Jeong, Kim, Tae Nyun, Kim, Mi Kyung, Park, Jeong Hyun, Rhee, Byoung Doo, Lee, Soon Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343135/ https://www.ncbi.nlm.nih.gov/pubmed/30729133 http://dx.doi.org/10.1155/2019/2376512 |
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