Cargando…

Hypoxia-Activated PI3K/Akt Inhibits Oxidative Stress via the Regulation of Reactive Oxygen Species in Human Dental Pulp Cells

In order to use stem cells as a resource for tissue regeneration, it is necessary to induce expansion in vitro. However, during culture, stem cells often lose functional properties and become senescent. Increasing evidence indicates that hypoxic preconditioning with physiological oxygen concentratio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Fei, Huang, Xin, Luo, Zhenhua, He, Jingjun, Haider, Farhan, Song, Ci, Peng, Ling, Chen, Ting, Wu, Buling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343138/ https://www.ncbi.nlm.nih.gov/pubmed/30728888 http://dx.doi.org/10.1155/2019/6595189

Ejemplares similares

A novel hypoxic lncRNA, HRL-SC, promotes the proliferation and migration of human dental pulp stem cells through the PI3K/AKT signaling pathway
por: Zeng, Junkai, et al.
Publicado: (2022)

Both Hypoxia-Inducible Factor 1 and MAPK Signaling Pathway Attenuate PI3K/AKT via Suppression of Reactive Oxygen Species in Human Pluripotent Stem Cells
por: Fojtík, Petr, et al.
Publicado: (2021)

Inactivation of PI3K/Akt promotes the odontoblastic differentiation and suppresses the stemness with autophagic flux in dental pulp cells
por: Park, Sam Young, et al.
Publicado: (2022)

Soyasaponins Can Blunt Inflammation by Inhibiting the Reactive Oxygen Species-Mediated Activation of PI3K/Akt/NF-kB Pathway
por: Zha, Longying, et al.
Publicado: (2014)

Antitumor effect of manumycin on colorectal cancer cells by increasing the reactive oxygen species production and blocking PI3K-AKT pathway
por: Zhang, Jingyu, et al.
Publicado: (2016)

Sparstolonin B exerts beneficial effects on prostate cancer by acting on the reactive oxygen species‐mediated PI3K/AKT pathway
por: Liu, Shaozhuang, et al.
Publicado: (2021)

Apatinib Promotes Apoptosis of Pancreatic Cancer Cells through Downregulation of Hypoxia-Inducible Factor-1α and Increased Levels of Reactive Oxygen Species
por: He, Ke, et al.
Publicado: (2019)

Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator-Induced Lung Injury
por: Spassov, Sashko Georgiev, et al.
Publicado: (2017)

Dihydroaustrasulfone alcohol induces apoptosis in nasopharyngeal cancer cells by inducing reactive oxygen species-dependent inactivation of the PI3K/AKT pathway
por: Tan, Kok-Tong, et al.
Publicado: (2023)

circRNA Expression Profile in Dental Pulp Stem Cells during Odontogenic Differentiation
por: Chen, Ming, et al.
Publicado: (2020)

Application of Reactive Oxygen Species in Dental Treatment
por: Komine, Chiaki, et al.
Publicado: (2022)

N-Acetyl Cysteine Depletes Reactive Oxygen Species and Prevents Dental Monomer-Induced Intrinsic Mitochondrial Apoptosis In Vitro in Human Dental Pulp Cells
por: Jiao, Yang, et al.
Publicado: (2016)

Withaferin A-Caused Production of Intracellular Reactive Oxygen Species Modulates Apoptosis via PI3K/Akt and JNKinase in Rabbit Articular Chondrocytes
por: Yu, Seon-Mi, et al.
Publicado: (2014)

Silymarin Protects Mouse Liver and Kidney from Thioacetamide Induced Toxicity by Scavenging Reactive Oxygen Species and Activating PI3K-Akt Pathway
por: Ghosh, Shatadal, et al.
Publicado: (2016)

Reactive oxygen species generation mediated by NADPH oxidase and PI3K/Akt pathways contribute to invasion of Streptococcus agalactiae in human endothelial cells
por: de Oliveira, Jessica Silva Santos, et al.
Publicado: (2018)

Corrigendum to “Hydrogen Sulfide Prevents Formation of Reactive Oxygen Species through PI3K/Akt Signaling and Limits Ventilator-Induced Lung Injury”
por: Spassov, Sashko Georgiev, et al.
Publicado: (2017)

PI3K/Akt and HIF-1 signaling pathway in hypoxia-ischemia
por: Zhang, Zhen, et al.
Publicado: (2018)

PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia
por: Xie, Youbang, et al.
Publicado: (2019)

Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?
por: Görlach, Agnes, et al.
Publicado: (2015)

Reactive Oxygen Species and Pulmonary Vasculature During Hypobaric Hypoxia
por: Siques, Patricia, et al.
Publicado: (2018)

ETV2 promotes osteogenic differentiation of human dental pulp stem cells through the ERK/MAPK and PI3K-Akt signaling pathways
por: Li, Jing, et al.
Publicado: (2022)

2-hydroxyethyl methacrylate-derived reactive oxygen species stimulate ATP release via TRPA1 in human dental pulp cells
por: Orimoto, Ai, et al.
Publicado: (2022)

Cytotoxicity and Effects of a New Cacium Hydroxide Nanoparticle Material on Production of Reactive Oxygen Species by LPS-Stimulated Dental Pulp Cells
por: de Souza, Gabriela Leite, et al.
Publicado: (2020)

Effect of LncRNA-MALAT1 on mineralization of dental pulp cells in a high-glucose microenvironment
por: Li, Xinzhu, et al.
Publicado: (2022)

Characterization of stable hypoxia-preconditioned dental pulp stem cells compared with mobilized dental pulp stem cells for application for pulp regenerative therapy
por: Zayed, Mohammed, et al.
Publicado: (2021)

HDAC inhibitor LMK-235 promotes the odontoblast differentiation of dental pulp cells
por: Liu, Zhao, et al.
Publicado: (2018)

Proteomic Analysis of Mesenchymal Stem Cells from Normal and Deep Carious Dental Pulp
por: Ma, Dandan, et al.
Publicado: (2014)

8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway
por: Xue, Yucong, et al.
Publicado: (2021)

Decellularized Swine Dental Pulp as a Bioscaffold for Pulp Regeneration
por: Hu, Lei, et al.
Publicado: (2017)

Stathmin inhibits proliferation and differentiation of dental pulp stem cells via sonic hedgehog/Gli
por: Ma, Dandan, et al.
Publicado: (2018)

Mitochondrial Reactive Oxygen Species and Kidney Hypoxia in the Development of Diabetic Nephropathy
por: Schiffer, Tomas A., et al.
Publicado: (2017)

Reactive Oxygen Species via Redox Signaling to PI3K/AKT Pathway Contribute to the Malignant Growth of 4-Hydroxy Estradiol-Transformed Mammary Epithelial Cells
por: Okoh, Victor O., et al.
Publicado: (2013)

p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling
por: Zhang, Yize, et al.
Publicado: (2019)

Dental pulp stem cells from human teeth with deep caries displayed an enhanced angiogenesis potential in vitro
por: Chen, Yan, et al.
Publicado: (2021)

N-Cadherin Regulates the Odontogenic Differentiation of Dental Pulp Stem Cells via β-Catenin Activity
por: Deng, Zilong, et al.
Publicado: (2021)

Reactive Oxygen Species Formation in the Brain at Different Oxygen Levels: The Role of Hypoxia Inducible Factors
por: Chen, Ruoli, et al.
Publicado: (2018)

Hypoxia regulates reactive oxygen species levels in SHG-44 glioma cells
por: Jiang, Haitao, et al.
Publicado: (2013)

The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression
por: Tafani, Marco, et al.
Publicado: (2016)

Simvastatin treatment promotes proliferation of human dental pulp stem cells via modulating PI3K/AKT/miR‐9/KLF5 signalling pathway
por: Wang, Jing‐hui, et al.
Publicado: (2021)

High Density Lipoprotein Protects Mesenchymal Stem Cells from Oxidative Stress-Induced Apoptosis via Activation of the PI3K/Akt Pathway and Suppression of Reactive Oxygen Species
por: Xu, Jianfeng, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2412fe0tj3vu46ek8on64v04k4