Geranylgeraniol (GGOH) as a Mevalonate Pathway Activator in the Rescue of Bone Cells Treated with Zoledronic Acid: An In Vitro Study

Bisphosphonates (BPs) are the keystone to treat bone disorders. Despite the great benefits of BPs, medication-related osteonecrosis of the jaw (MRONJ) arouse as a potential side effect. Nitrogen-containing BPs (N-BPs) as zoledronate (ZA) act by the inhibition of specific enzymes of the mevalonate pa...

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Detalles Bibliográficos
Autores principales: Fliefel, Riham M., Entekhabi, Saleh A., Ehrenfeld, Michael, Otto, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343170/
https://www.ncbi.nlm.nih.gov/pubmed/30728841
http://dx.doi.org/10.1155/2019/4351327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343170/
https://www.ncbi.nlm.nih.gov/pubmed/30728841
http://dx.doi.org/10.1155/2019/4351327

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