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Geranylgeraniol (GGOH) as a Mevalonate Pathway Activator in the Rescue of Bone Cells Treated with Zoledronic Acid: An In Vitro Study

Bisphosphonates (BPs) are the keystone to treat bone disorders. Despite the great benefits of BPs, medication-related osteonecrosis of the jaw (MRONJ) arouse as a potential side effect. Nitrogen-containing BPs (N-BPs) as zoledronate (ZA) act by the inhibition of specific enzymes of the mevalonate pa...

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Detalles Bibliográficos
Autores principales:	Fliefel, Riham M., Entekhabi, Saleh A., Ehrenfeld, Michael, Otto, Sven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343170/ https://www.ncbi.nlm.nih.gov/pubmed/30728841 http://dx.doi.org/10.1155/2019/4351327

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