Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway

BACKGROUND: Rhein is a lipophilic anthraquinone extensively found in medicinal herbs. Emerging evidence suggests that rhein has significant antitumor effects, supporting its potential use as an antitumor agent. The IL6/STAT3 signaling pathway has been suggested as an attractive target for the discov...

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Detalles Bibliográficos
Autores principales: Yang, Lehe, Lin, Shichong, Kang, Yanting, Xiang, Youqun, Xu, Lingyuan, Li, Jifa, Dai, Xuanxuan, Liang, Guang, Huang, Xiaoying, Zhao, Chengguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343257/
https://www.ncbi.nlm.nih.gov/pubmed/30674340
http://dx.doi.org/10.1186/s13046-018-1015-9

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