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Diagnostic yield and clinical utility of a comprehensive gene panel for hereditary tumor syndromes
BACKGROUND: In a considerable number of patients with a suspected hereditary tumor syndrome (HTS), no underlying germline mutation is detected in the most likely affected genes. The present study aimed to establish and validate a large gene panel for HTS, and determine its diagnostic yield and clini...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343270/ https://www.ncbi.nlm.nih.gov/pubmed/30680046 http://dx.doi.org/10.1186/s13053-018-0102-4 |