Cargando…

First-line HIV treatment failures in non-B subtypes and recombinants: a cross-sectional analysis of multiple populations in Uganda

BACKGROUND: Our understanding of HIV-1 and antiretroviral treatment (ART) is strongly biased towards subtype B, the predominant subtype in North America and western Europe. Efforts to characterize the response to first-line treatments in other HIV-1 subtypes have been hindered by the availability of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poon, Art F. Y., Ndashimye, Emmanuel, Avino, Mariano, Gibson, Richard, Kityo, Cissy, Kyeyune, Fred, Nankya, Immaculate, Quiñones-Mateu, Miguel E., ARTS, Eric J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343277/ https://www.ncbi.nlm.nih.gov/pubmed/30670037 http://dx.doi.org/10.1186/s12981-019-0218-2

Ejemplares similares

Sensitive detection of HIV-1 resistance to Zidovudine and impact on treatment outcomes in low- to middle-income countries
por: Gibson, Richard M., et al.
Publicado: (2017)

Comparison of HIV drug resistance profiles across HIV-1 subtypes A and D for patients receiving a tenofovir-based and zidovudine-based first line regimens in Uganda
por: Ayitewala, Alisen, et al.
Publicado: (2020)

HIV Drug Resistance Mutations in Non-B Subtypes After Prolonged Virological Failure on NNRTI-Based First-Line Regimens in Sub-Saharan Africa
por: Kityo, Cissy, et al.
Publicado: (2017)

Reduced and highly diverse peripheral HIV-1 reservoir in virally suppressed patients infected with non-B HIV-1 strains in Uganda
por: Joussef-Piña, Samira, et al.
Publicado: (2022)

Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection
por: Klein, Katja, et al.
Publicado: (2018)

Defining the fitness of HIV-1 isolates with dual/mixed co-receptor usage
por: Nankya, Immaculate L, et al.
Publicado: (2015)

HIV Drug Resistance Among Children Initiating First-Line Antiretroviral Treatment in Uganda
por: Kityo, Cissy, et al.
Publicado: (2016)

An open-source k-mer based machine learning tool for fast and accurate subtyping of HIV-1 genomes
por: Solis-Reyes, Stephen, et al.
Publicado: (2018)

Infecting HIV-1 Subtype Predicts Disease Progression in Women of Sub-Saharan Africa
por: Venner, Colin M., et al.
Publicado: (2016)

Hepatitis C in Uganda: Identification of infected blood donors for micro-elimination
por: Nankya-Mutyoba, Joan, et al.
Publicado: (2021)

The urgent need for more potent antiretroviral therapy in low-income countries to achieve UNAIDS 90-90-90 and complete eradication of AIDS by 2030
por: Ndashimye, Emmanuel, et al.
Publicado: (2019)

Evidence for a recombinant origin of HIV-1 Group M from genomic variation
por: Olabode, Abayomi S, et al.
Publicado: (2019)

Virologic versus immunologic monitoring and the rate of accumulated genotypic resistance to first-line antiretroviral drugs in Uganda
por: Reynolds, Steven J, et al.
Publicado: (2012)

Nucleoside reverse-transcriptase inhibitor cross-resistance and outcomes from second-line antiretroviral therapy in the public health approach: an observational analysis within the randomised, open-label, EARNEST trial
por: Paton, Nicholas I, et al.
Publicado: (2017)

Differences in Clinical Manifestations of Acute and Early HIV-1 Infection between HIV-1 Subtypes in African Women
por: Lemonovich, Tracy L., et al.
Publicado: (2015)

Identification of gaps for implementation science in the HIV prevention, care and treatment cascade; a qualitative study in 19 districts in Uganda
por: Bajunirwe, Francis, et al.
Publicado: (2016)

Long-Term Antiretroviral Treatment Adherence in HIV-Infected Adolescents and Adults in Uganda: A Qualitative Study
por: Inzaule, Seth C., et al.
Publicado: (2016)

Correction: Long-Term Antiretroviral Treatment Adherence in HIV-Infected Adolescents and Adults in Uganda: A Qualitative Study
por: Inzaule, Seth C., et al.
Publicado: (2017)

Persistence of traditional and emergence of new structural drivers and factors for the HIV epidemic in rural Uganda; A qualitative study
por: Bajunirwe, Francis, et al.
Publicado: (2019)

Reduced CCR5 expression among Uganda HIV controllers
por: Nyiro, Brian, et al.
Publicado: (2023)

Circulating plasma NT-proBNP predicts subclinical coronary atherosclerosis on CT angiography among older adults in Uganda
por: Shakil, Saate S, et al.
Publicado: (2023)

Sex, HIV Status, and Measures of Cardiac Stress and Fibrosis in Uganda
por: Kipke, Jasmine, et al.
Publicado: (2021)

Efficacy of convalescent plasma for treatment of COVID-19 in Uganda
por: Kirenga, Bruce, et al.
Publicado: (2021)

Clinical Evaluation of an Affordable Qualitative Viral Failure Assay for HIV Using Dried Blood Spots in Uganda
por: Balinda, Sheila N., et al.
Publicado: (2016)

Tree shape‐based approaches for the comparative study of cophylogeny
por: Avino, Mariano, et al.
Publicado: (2019)

Sex-specific performance of the ASCVD pooled cohort equation risk calculator as a correlate of coronary artery calcium in Kampala, Uganda
por: Kentoffio, Katherine, et al.
Publicado: (2022)

Coronary artery calcium, HIV and inflammation in Uganda compared with the USA
por: Alencherry, Ben, et al.
Publicado: (2019)

Phylogenetic measures of indel rate variation among the HIV-1 group M subtypes
por: Palmer, John, et al.
Publicado: (2019)

Specialized DNA Structures Act as Genomic Beacons for Integration by Evolutionarily Diverse Retroviruses
por: Kohio, Hinissan P., et al.
Publicado: (2023)

A Sex-Stratified Analysis of Monocyte Phenotypes Associated with HIV Infection in Uganda
por: Huaman, Moises A., et al.
Publicado: (2021)

A Human-Centered Approach to CV Care: Infrastructure Development in Uganda
por: Longenecker, Christopher T., et al.
Publicado: (2018)

Positive predictive value and effectiveness of measles case-based surveillance in Uganda, 2012-2015
por: Nsubuga, Fred, et al.
Publicado: (2017)

HIV-1 strains belonging to large phylogenetic clusters show accelerated escape from integrase inhibitors in cell culture compared with viral isolates from singleton/small clusters
por: Brenner, Bluma G., et al.
Publicado: (2017)

Role of co-expressed APOBEC3F and APOBEC3G in inducing HIV-1 drug resistance
por: Mohammadzadeh, Nazanin, et al.
Publicado: (2019)

Factors that affect immunization data quality in Kabarole District, Uganda
por: Nsubuga, Fred, et al.
Publicado: (2018)

Improving blood transfusion safety in resource-poor countries: a case study of using leucocyte reduced blood in Uganda
por: Dhabangi, Aggrey, et al.
Publicado: (2020)

Determinants of Clinician Knowledge on Aging and HIV/AIDS: A Survey of Practitioners and Policy Makers in Kampala District, Uganda
por: Obuku, Ekwaro A., et al.
Publicado: (2013)

Mortality in the Year Following Antiretroviral Therapy Initiation in HIV-Infected Adults and Children in Uganda and Zimbabwe
por: Walker, A. Sarah, et al.
Publicado: (2012)

Therapeutic drug monitoring of nevirapine in saliva in Uganda using high performance liquid chromatography and a low cost thin-layer chromatography technique
por: Lamorde, Mohammed, et al.
Publicado: (2014)

Impact of second-line antiretroviral regimens on lipid profiles in an African setting: the DART trial sub-study
por: Gomo, Zvenyika AR, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4is9jnv3fek3eb12p340rrtjk1