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Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer

BACKGROUND: The management of pancreatic cancer (PanCa) is exceptionally difficult due to poor response to available therapeutic modalities. Tubulins play a major role in cell dynamics, thus are important molecular targets for cancer therapy. Among various tubulins, βIII and βIV-tubulin isoforms hav...

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Detalles Bibliográficos
Autores principales: Kashyap, Vivek K., Wang, Qinghui, Setua, Saini, Nagesh, Prashanth K. B., Chauhan, Neeraj, Kumari, Sonam, Chowdhury, Pallabita, Miller, Duane D., Yallapu, Murali M., Li, Wei, Jaggi, Meena, Hafeez, Bilal Bin, Chauhan, Subhash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343279/
https://www.ncbi.nlm.nih.gov/pubmed/30674344
http://dx.doi.org/10.1186/s13046-018-1009-7

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