LRRK2 is involved in the pathogenesis of system lupus erythematosus through promoting pathogenic antibody production

BACKGROUND: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by the presence of pathogenic autoantibodies associated with polyclonal B cell hyperreactivity. Previous study reported that autophagy-related gene Leucine-rich repeat kinase 2 (LRRK2) was likely a suscep...

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Detalles Bibliográficos
Autores principales: Zhang, Meiyu, Yao, Chengcheng, Cai, Jun, Liu, Shuai, Liu, Xia-nan, Chen, Yingying, Wang, Shujun, Ji, Ping, Pan, Meng, Kang, Zizhen, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343316/
https://www.ncbi.nlm.nih.gov/pubmed/30670047
http://dx.doi.org/10.1186/s12967-019-1786-6

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