JAK/Stat5-mediated subtype-specific lymphocyte antigen 6 complex, locus G6D (LY6G6D) expression drives mismatch repair proficient colorectal cancer

BACKGROUND: Human microsatellite-stable (MSS) colorectal cancers (CRCs) are immunologically “cold” tumour subtypes characterized by reduced immune cytotoxicity. The molecular linkages between immune-resistance and human MSS CRC is not clear. METHODS: We used transcriptome profiling, in silico analys...

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Detalles Bibliográficos
Autores principales: Giordano, Guido, Parcesepe, Pietro, D’Andrea, Mario Rosario, Coppola, Luigi, Di Raimo, Tania, Remo, Andrea, Manfrin, Erminia, Fiorini, Claudia, Scarpa, Aldo, Amoreo, Carla Azzurra, Conciatori, Fabiana, Milella, Michele, Caruso, Francesca Pia, Cerulo, Luigi, Porras, Almudena, Pancione, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343337/
https://www.ncbi.nlm.nih.gov/pubmed/30670049
http://dx.doi.org/10.1186/s13046-018-1019-5

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