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Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
BACKGROUND: A deep learning computer artificial intelligence system is helpful for early identification of ground glass opacities (GGOs). METHODS: Images from the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) database were used in AlexNet and GoogLeNet to detect p...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343356/ https://www.ncbi.nlm.nih.gov/pubmed/30670024 http://dx.doi.org/10.1186/s12938-019-0627-4 |
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author | Ye, Wenjing Gu, Wen Guo, Xuejun Yi, Ping Meng, Yishuang Han, Fengfeng Yu, Lingwei Chen, Yi Zhang, Guorui Wang, Xueting |
author_facet | Ye, Wenjing Gu, Wen Guo, Xuejun Yi, Ping Meng, Yishuang Han, Fengfeng Yu, Lingwei Chen, Yi Zhang, Guorui Wang, Xueting |
author_sort | Ye, Wenjing |
collection | PubMed |
description | BACKGROUND: A deep learning computer artificial intelligence system is helpful for early identification of ground glass opacities (GGOs). METHODS: Images from the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) database were used in AlexNet and GoogLeNet to detect pulmonary nodules, and 221 GGO images provided by Xinhua Hospital were used in ResNet50 for detecting GGOs. We used computed tomography image radial reorganization to create the input image of the three-dimensional features, and used the extracted features for deep learning, network training, testing, and analysis. RESULTS: In the final evaluation results, we found that the accuracy of identification of lung nodule could reach 88.0%, with an F-score of 0.891. In terms of performance and accuracy, our method was better than the existing solutions. The GGO nodule classification achieved the best F-score of 0.87805. We propose a preprocessing method of red, green, and blue (RGB) superposition in the region of interest to effectively increase the differentiation between nodules and normal tissues, and that is the innovation of our research. CONCLUSIONS: The method of deep learning proposed in this study is more sensitive than other systems in recent years, and the average false positive is lower than that of others. |
format | Online Article Text |
id | pubmed-6343356 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-63433562019-01-24 Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence Ye, Wenjing Gu, Wen Guo, Xuejun Yi, Ping Meng, Yishuang Han, Fengfeng Yu, Lingwei Chen, Yi Zhang, Guorui Wang, Xueting Biomed Eng Online Research BACKGROUND: A deep learning computer artificial intelligence system is helpful for early identification of ground glass opacities (GGOs). METHODS: Images from the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) database were used in AlexNet and GoogLeNet to detect pulmonary nodules, and 221 GGO images provided by Xinhua Hospital were used in ResNet50 for detecting GGOs. We used computed tomography image radial reorganization to create the input image of the three-dimensional features, and used the extracted features for deep learning, network training, testing, and analysis. RESULTS: In the final evaluation results, we found that the accuracy of identification of lung nodule could reach 88.0%, with an F-score of 0.891. In terms of performance and accuracy, our method was better than the existing solutions. The GGO nodule classification achieved the best F-score of 0.87805. We propose a preprocessing method of red, green, and blue (RGB) superposition in the region of interest to effectively increase the differentiation between nodules and normal tissues, and that is the innovation of our research. CONCLUSIONS: The method of deep learning proposed in this study is more sensitive than other systems in recent years, and the average false positive is lower than that of others. BioMed Central 2019-01-22 /pmc/articles/PMC6343356/ /pubmed/30670024 http://dx.doi.org/10.1186/s12938-019-0627-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Ye, Wenjing Gu, Wen Guo, Xuejun Yi, Ping Meng, Yishuang Han, Fengfeng Yu, Lingwei Chen, Yi Zhang, Guorui Wang, Xueting Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence |
title | Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence |
title_full | Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence |
title_fullStr | Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence |
title_full_unstemmed | Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence |
title_short | Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence |
title_sort | detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343356/ https://www.ncbi.nlm.nih.gov/pubmed/30670024 http://dx.doi.org/10.1186/s12938-019-0627-4 |
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