Cargando…

Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence

BACKGROUND: A deep learning computer artificial intelligence system is helpful for early identification of ground glass opacities (GGOs). METHODS: Images from the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) database were used in AlexNet and GoogLeNet to detect p...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Wenjing, Gu, Wen, Guo, Xuejun, Yi, Ping, Meng, Yishuang, Han, Fengfeng, Yu, Lingwei, Chen, Yi, Zhang, Guorui, Wang, Xueting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343356/
https://www.ncbi.nlm.nih.gov/pubmed/30670024
http://dx.doi.org/10.1186/s12938-019-0627-4
_version_ 1783389271432888320
author Ye, Wenjing
Gu, Wen
Guo, Xuejun
Yi, Ping
Meng, Yishuang
Han, Fengfeng
Yu, Lingwei
Chen, Yi
Zhang, Guorui
Wang, Xueting
author_facet Ye, Wenjing
Gu, Wen
Guo, Xuejun
Yi, Ping
Meng, Yishuang
Han, Fengfeng
Yu, Lingwei
Chen, Yi
Zhang, Guorui
Wang, Xueting
author_sort Ye, Wenjing
collection PubMed
description BACKGROUND: A deep learning computer artificial intelligence system is helpful for early identification of ground glass opacities (GGOs). METHODS: Images from the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) database were used in AlexNet and GoogLeNet to detect pulmonary nodules, and 221 GGO images provided by Xinhua Hospital were used in ResNet50 for detecting GGOs. We used computed tomography image radial reorganization to create the input image of the three-dimensional features, and used the extracted features for deep learning, network training, testing, and analysis. RESULTS: In the final evaluation results, we found that the accuracy of identification of lung nodule could reach 88.0%, with an F-score of 0.891. In terms of performance and accuracy, our method was better than the existing solutions. The GGO nodule classification achieved the best F-score of 0.87805. We propose a preprocessing method of red, green, and blue (RGB) superposition in the region of interest to effectively increase the differentiation between nodules and normal tissues, and that is the innovation of our research. CONCLUSIONS: The method of deep learning proposed in this study is more sensitive than other systems in recent years, and the average false positive is lower than that of others.
format Online
Article
Text
id pubmed-6343356
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-63433562019-01-24 Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence Ye, Wenjing Gu, Wen Guo, Xuejun Yi, Ping Meng, Yishuang Han, Fengfeng Yu, Lingwei Chen, Yi Zhang, Guorui Wang, Xueting Biomed Eng Online Research BACKGROUND: A deep learning computer artificial intelligence system is helpful for early identification of ground glass opacities (GGOs). METHODS: Images from the Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) database were used in AlexNet and GoogLeNet to detect pulmonary nodules, and 221 GGO images provided by Xinhua Hospital were used in ResNet50 for detecting GGOs. We used computed tomography image radial reorganization to create the input image of the three-dimensional features, and used the extracted features for deep learning, network training, testing, and analysis. RESULTS: In the final evaluation results, we found that the accuracy of identification of lung nodule could reach 88.0%, with an F-score of 0.891. In terms of performance and accuracy, our method was better than the existing solutions. The GGO nodule classification achieved the best F-score of 0.87805. We propose a preprocessing method of red, green, and blue (RGB) superposition in the region of interest to effectively increase the differentiation between nodules and normal tissues, and that is the innovation of our research. CONCLUSIONS: The method of deep learning proposed in this study is more sensitive than other systems in recent years, and the average false positive is lower than that of others. BioMed Central 2019-01-22 /pmc/articles/PMC6343356/ /pubmed/30670024 http://dx.doi.org/10.1186/s12938-019-0627-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Ye, Wenjing
Gu, Wen
Guo, Xuejun
Yi, Ping
Meng, Yishuang
Han, Fengfeng
Yu, Lingwei
Chen, Yi
Zhang, Guorui
Wang, Xueting
Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
title Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
title_full Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
title_fullStr Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
title_full_unstemmed Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
title_short Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
title_sort detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343356/
https://www.ncbi.nlm.nih.gov/pubmed/30670024
http://dx.doi.org/10.1186/s12938-019-0627-4
work_keys_str_mv AT yewenjing detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT guwen detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT guoxuejun detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT yiping detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT mengyishuang detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT hanfengfeng detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT yulingwei detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT chenyi detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT zhangguorui detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence
AT wangxueting detectionofpulmonarygroundglassopacitybasedondeeplearningcomputerartificialintelligence