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Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges
Intrathoracic lymphadenopathy is a common problem encountered in clinical practice and is caused by a wide variety of diseases. Traditionally, the mediastinal lymph nodes were sampled using conventional transbronchial needle aspiration (TBNA), or surgical methods such as mediastinoscopy, and thoraco...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343395/ https://www.ncbi.nlm.nih.gov/pubmed/30745744 http://dx.doi.org/10.4103/JOC.JOC_171_18 |
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author | Muthu, Valliappan Sehgal, Inderpaul Singh Dhooria, Sahajal Prasad, Kuruswamy T. Gupta, Nalini Aggarwal, Ashutosh N. Agarwal, Ritesh |
author_facet | Muthu, Valliappan Sehgal, Inderpaul Singh Dhooria, Sahajal Prasad, Kuruswamy T. Gupta, Nalini Aggarwal, Ashutosh N. Agarwal, Ritesh |
author_sort | Muthu, Valliappan |
collection | PubMed |
description | Intrathoracic lymphadenopathy is a common problem encountered in clinical practice and is caused by a wide variety of diseases. Traditionally, the mediastinal lymph nodes were sampled using conventional transbronchial needle aspiration (TBNA), or surgical methods such as mediastinoscopy, and thoracotomy (open or video-assisted thoracoscopy). However, surgical modalities including mediastinoscopy are invasive, expensive, and not universally available. Moreover, they are associated with considerable morbidity and mortality. Conventional TBNA although minimally invasive has a low diagnostic yield. In the last decade, endobronchial ultrasound-guided TBNA (EBUS-TBNA) has emerged as the diagnostic procedure of choice in evaluating undiagnosed intrathoracic lymphadenopathy. EBUS-TBNA is also currently the preferred modality in the mediastinal staging of lung cancer. The procedure is minimally invasive, safe, and can be performed as a day-care procedure. In the era of personalized medicine in lung cancer, optimizing the procedure, sample collection, and processing are crucial, as more tissue is required for performing a wide array of molecular tests. Despite its widespread use and acceptance, the diagnostic sensitivity of EBUS-TBNA is still low. To maximize the yield, cytologists and physicians should be aware of the technical details of the procedure. Herein, we discuss the technique of performing EBUS-TBNA, its indications, contraindications, and the processing of the samples at our bronchoscopy suite. We also highlight the challenges faced by the cytologists and clinicians while processing EBUS aspirates. |
format | Online Article Text |
id | pubmed-6343395 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-63433952019-02-11 Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges Muthu, Valliappan Sehgal, Inderpaul Singh Dhooria, Sahajal Prasad, Kuruswamy T. Gupta, Nalini Aggarwal, Ashutosh N. Agarwal, Ritesh J Cytol Symposium Intrathoracic lymphadenopathy is a common problem encountered in clinical practice and is caused by a wide variety of diseases. Traditionally, the mediastinal lymph nodes were sampled using conventional transbronchial needle aspiration (TBNA), or surgical methods such as mediastinoscopy, and thoracotomy (open or video-assisted thoracoscopy). However, surgical modalities including mediastinoscopy are invasive, expensive, and not universally available. Moreover, they are associated with considerable morbidity and mortality. Conventional TBNA although minimally invasive has a low diagnostic yield. In the last decade, endobronchial ultrasound-guided TBNA (EBUS-TBNA) has emerged as the diagnostic procedure of choice in evaluating undiagnosed intrathoracic lymphadenopathy. EBUS-TBNA is also currently the preferred modality in the mediastinal staging of lung cancer. The procedure is minimally invasive, safe, and can be performed as a day-care procedure. In the era of personalized medicine in lung cancer, optimizing the procedure, sample collection, and processing are crucial, as more tissue is required for performing a wide array of molecular tests. Despite its widespread use and acceptance, the diagnostic sensitivity of EBUS-TBNA is still low. To maximize the yield, cytologists and physicians should be aware of the technical details of the procedure. Herein, we discuss the technique of performing EBUS-TBNA, its indications, contraindications, and the processing of the samples at our bronchoscopy suite. We also highlight the challenges faced by the cytologists and clinicians while processing EBUS aspirates. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6343395/ /pubmed/30745744 http://dx.doi.org/10.4103/JOC.JOC_171_18 Text en Copyright: © 2019 Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Symposium Muthu, Valliappan Sehgal, Inderpaul Singh Dhooria, Sahajal Prasad, Kuruswamy T. Gupta, Nalini Aggarwal, Ashutosh N. Agarwal, Ritesh Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges |
title | Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges |
title_full | Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges |
title_fullStr | Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges |
title_full_unstemmed | Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges |
title_short | Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges |
title_sort | endobronchial ultrasound-guided transbronchial needle aspiration: techniques and challenges |
topic | Symposium |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343395/ https://www.ncbi.nlm.nih.gov/pubmed/30745744 http://dx.doi.org/10.4103/JOC.JOC_171_18 |
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