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Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases

Cysticercosis is a systemic parasitic disease caused by larval stage of Taenia solium. It is the most common parasitic disease worldwide. It is potentially a dangerous systemic disease with variable clinical manifestations. It can be diagnosed by radiological imaging and serology but demonstration o...

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Autores principales: Bhardwaj, Subhash, Rather, Gousia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343397/
https://www.ncbi.nlm.nih.gov/pubmed/30745734
http://dx.doi.org/10.4103/JOC.JOC_77_17
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author Bhardwaj, Subhash
Rather, Gousia
author_facet Bhardwaj, Subhash
Rather, Gousia
author_sort Bhardwaj, Subhash
collection PubMed
description Cysticercosis is a systemic parasitic disease caused by larval stage of Taenia solium. It is the most common parasitic disease worldwide. It is potentially a dangerous systemic disease with variable clinical manifestations. It can be diagnosed by radiological imaging and serology but demonstration of parasitic larva by cytology or histopathology is still the gold standard. Fine needle aspiration cytology (FNAC) plays an important role in prompt diagnosis of this disease. AIM: To study the role of FNAC in the diagnosis of cysticercosis. MATERIALS AND METHODS: This study included 30 patients presenting with palpable subcutaneous and intramuscular nodules at different sites. Fine needle aspiration was performed on these lesions and cytological features were analyzed. Subsequent excision biopsy was evaluated wherever possible. RESULTS: Thirty patients in the age group of 7–80 years presenting with subcutaneous and intramuscular nodules at various sites were studied. Majority of the patients were males. The most commonly affected sites were upper and lower extremities and abdominal wall. Most of the cases were clinically misdiagnosed as lipomas, neurofibromas, lymphadenitis, epidermal inclusion cyst, sialadenitis, and soft tissue tumors. On cytological examination of aspirate from the lesions, fragments of parasite were seen in a background of mixed inflammatory cell infiltrate. Histopathological correlation was available in 17 cases. CONCLUSION: FNAC is a simple, sensitive, cost-effective, and rapid diagnostic tool for diagnosis of cysticercosis as cytological diagnosis is quite clear where the actual parasitic structures are identified in the smear.
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spelling pubmed-63433972019-02-11 Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases Bhardwaj, Subhash Rather, Gousia J Cytol Original Article Cysticercosis is a systemic parasitic disease caused by larval stage of Taenia solium. It is the most common parasitic disease worldwide. It is potentially a dangerous systemic disease with variable clinical manifestations. It can be diagnosed by radiological imaging and serology but demonstration of parasitic larva by cytology or histopathology is still the gold standard. Fine needle aspiration cytology (FNAC) plays an important role in prompt diagnosis of this disease. AIM: To study the role of FNAC in the diagnosis of cysticercosis. MATERIALS AND METHODS: This study included 30 patients presenting with palpable subcutaneous and intramuscular nodules at different sites. Fine needle aspiration was performed on these lesions and cytological features were analyzed. Subsequent excision biopsy was evaluated wherever possible. RESULTS: Thirty patients in the age group of 7–80 years presenting with subcutaneous and intramuscular nodules at various sites were studied. Majority of the patients were males. The most commonly affected sites were upper and lower extremities and abdominal wall. Most of the cases were clinically misdiagnosed as lipomas, neurofibromas, lymphadenitis, epidermal inclusion cyst, sialadenitis, and soft tissue tumors. On cytological examination of aspirate from the lesions, fragments of parasite were seen in a background of mixed inflammatory cell infiltrate. Histopathological correlation was available in 17 cases. CONCLUSION: FNAC is a simple, sensitive, cost-effective, and rapid diagnostic tool for diagnosis of cysticercosis as cytological diagnosis is quite clear where the actual parasitic structures are identified in the smear. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6343397/ /pubmed/30745734 http://dx.doi.org/10.4103/JOC.JOC_77_17 Text en Copyright: © 2019 Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Bhardwaj, Subhash
Rather, Gousia
Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases
title Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases
title_full Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases
title_fullStr Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases
title_full_unstemmed Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases
title_short Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases
title_sort fine needle aspiration cytology of cysticercosis: a study of 30 cases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343397/
https://www.ncbi.nlm.nih.gov/pubmed/30745734
http://dx.doi.org/10.4103/JOC.JOC_77_17
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