Inhibition of PTEN activates bovine non-growing follicles in vitro but increases DNA damage and reduces DNA repair response

STUDY QUESTION: Does ovarian follicle activation by phosphatase homologue of chromosome-10 (PTEN) inhibition affect DNA damage and repair in bovine oocytes and granulosa cells? SUMMARY ANSWER: PTEN inhibition promotes bovine non-growing follicle activation but results in increased DNA damage and imp...

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Detalles Bibliográficos
Autores principales: Maidarti, Mila, Clarkson, Yvonne L, McLaughlin, Marie, Anderson, Richard A, Telfer, Evelyn E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343469/
https://www.ncbi.nlm.nih.gov/pubmed/30521029
http://dx.doi.org/10.1093/humrep/dey354

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