Cargando…

Role of radiotherapy in the treatment of metastatic head and neck cancer

In metastatic or locally advanced head and neck tumors that present in frail patients or after chemotherapy progression, radiotherapy is normally used as a palliative treatment, with a high rate of symptom palliation and improvement in quality of life. However, there is controversy about what the op...

Descripción completa

Detalles Bibliográficos
Autores principales: Ordoñez, Rafael, Otero, Ana, Jerez, Inmaculada, Medina, Jose A, Lupiañez-Pérez, Yolanda, Gomez-Millan, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343506/
https://www.ncbi.nlm.nih.gov/pubmed/30705596
http://dx.doi.org/10.2147/OTT.S181697
_version_ 1783389297832886272
author Ordoñez, Rafael
Otero, Ana
Jerez, Inmaculada
Medina, Jose A
Lupiañez-Pérez, Yolanda
Gomez-Millan, Jaime
author_facet Ordoñez, Rafael
Otero, Ana
Jerez, Inmaculada
Medina, Jose A
Lupiañez-Pérez, Yolanda
Gomez-Millan, Jaime
author_sort Ordoñez, Rafael
collection PubMed
description In metastatic or locally advanced head and neck tumors that present in frail patients or after chemotherapy progression, radiotherapy is normally used as a palliative treatment, with a high rate of symptom palliation and improvement in quality of life. However, there is controversy about what the optimal regimen is. Moreover, despite the poor prognosis of metastatic head and neck cancer, different retrospective studies have shown that a minority of patients with oligometastatic disease experience prolonged disease-free survival after adding curative radiotherapy treatment to the metastatic disease and/or primary tumor. Different retrospective studies have identified clinical prognostic factors that may be used to select candidate patients with metastatic head and neck cancer for a radical approach with radiotherapy. The purpose of this manuscript is to review the role of radiotherapy in metastatic and locally advanced head and neck tumors.
format Online
Article
Text
id pubmed-6343506
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-63435062019-01-31 Role of radiotherapy in the treatment of metastatic head and neck cancer Ordoñez, Rafael Otero, Ana Jerez, Inmaculada Medina, Jose A Lupiañez-Pérez, Yolanda Gomez-Millan, Jaime Onco Targets Ther Review In metastatic or locally advanced head and neck tumors that present in frail patients or after chemotherapy progression, radiotherapy is normally used as a palliative treatment, with a high rate of symptom palliation and improvement in quality of life. However, there is controversy about what the optimal regimen is. Moreover, despite the poor prognosis of metastatic head and neck cancer, different retrospective studies have shown that a minority of patients with oligometastatic disease experience prolonged disease-free survival after adding curative radiotherapy treatment to the metastatic disease and/or primary tumor. Different retrospective studies have identified clinical prognostic factors that may be used to select candidate patients with metastatic head and neck cancer for a radical approach with radiotherapy. The purpose of this manuscript is to review the role of radiotherapy in metastatic and locally advanced head and neck tumors. Dove Medical Press 2019-01-18 /pmc/articles/PMC6343506/ /pubmed/30705596 http://dx.doi.org/10.2147/OTT.S181697 Text en © 2019 Ordoñez et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Ordoñez, Rafael
Otero, Ana
Jerez, Inmaculada
Medina, Jose A
Lupiañez-Pérez, Yolanda
Gomez-Millan, Jaime
Role of radiotherapy in the treatment of metastatic head and neck cancer
title Role of radiotherapy in the treatment of metastatic head and neck cancer
title_full Role of radiotherapy in the treatment of metastatic head and neck cancer
title_fullStr Role of radiotherapy in the treatment of metastatic head and neck cancer
title_full_unstemmed Role of radiotherapy in the treatment of metastatic head and neck cancer
title_short Role of radiotherapy in the treatment of metastatic head and neck cancer
title_sort role of radiotherapy in the treatment of metastatic head and neck cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343506/
https://www.ncbi.nlm.nih.gov/pubmed/30705596
http://dx.doi.org/10.2147/OTT.S181697
work_keys_str_mv AT ordonezrafael roleofradiotherapyinthetreatmentofmetastaticheadandneckcancer
AT oteroana roleofradiotherapyinthetreatmentofmetastaticheadandneckcancer
AT jerezinmaculada roleofradiotherapyinthetreatmentofmetastaticheadandneckcancer
AT medinajosea roleofradiotherapyinthetreatmentofmetastaticheadandneckcancer
AT lupianezperezyolanda roleofradiotherapyinthetreatmentofmetastaticheadandneckcancer
AT gomezmillanjaime roleofradiotherapyinthetreatmentofmetastaticheadandneckcancer