Cargando…

A Synthetic, Small, Sulfated Agent Is a Promising Inhibitor of Chlamydia spp. Infection in vivo

Chlamydia is the most frequently reported sexually transmitted bacteria causing 2.9 million infections annually in the United States. Diagnosis, treatment, and sequelae of chlamydial disease cost billions of dollars each year in the United States alone. Considering that a heparin sulfate-like cell s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gallegos, Karen M., Taylor, Christopher R., Rabulinski, Daniel J., Del Toro, Rosalinda, Girgis, Danielle E., Jourha, Dapinder, Tiwari, Vaibhav, Desai, Umesh R., Ramsey, Kyle H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343517/ https://www.ncbi.nlm.nih.gov/pubmed/30700982 http://dx.doi.org/10.3389/fmicb.2018.03269

Ejemplares similares

Preferential recognition and antagonism of SARS-CoV-2 spike glycoprotein binding to 3-O-sulfated heparan sulfate
por: Tiwari, Vaibhav, et al.
Publicado: (2020)

Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors
por: Abdelfadiel, Elsamani I., et al.
Publicado: (2023)

A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules
por: Nagarajan, Balaji, et al.
Publicado: (2017)

The genetic basis of plasmid tropism between Chlamydia trachomatis and Chlamydia muridarum
por: Wang, Yibing, et al.
Publicado: (2014)

3-O-Sulfation induces sequence-specific compact topologies in heparan sulfate that encode a dynamic sulfation code
por: Holmes, Samuel G., et al.
Publicado: (2022)

Imiquimod Does not Affect Shedding of Viable Chlamydiae in a Murine Model of Chlamydia trachomatis Genital Tract Infection
por: Ramsey, Kyle H., et al.
Publicado: (2003)

Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity
por: Morla, Shravan, et al.
Publicado: (2023)

Discovery of Sulfated Small Molecule Inhibitors of Matrix Metalloproteinase-8
por: Morla, Shravan, et al.
Publicado: (2020)

The occurrence of Chlamydia spp. in pigs with and without clinical disease
por: Englund, Stina, et al.
Publicado: (2012)

Diversity of Heparan Sulfate and HSV Entry: Basic Understanding and Treatment Strategies
por: Tiwari, Vaibhav, et al.
Publicado: (2015)

Parachlamydia spp. and Related Chlamydia-like Organisms and Bovine Abortion
por: Borel, Nicole, et al.
Publicado: (2007)

Designing Allosteric Inhibitors of Factor XIa. Lessons from the Interactions of Sulfated Pentagalloylglucopyranosides
por: Al-Horani, Rami A., et al.
Publicado: (2014)

Plasmin Regulation through Allosteric, Sulfated, Small Molecules
por: Al-Horani, Rami A., et al.
Publicado: (2015)

HSV-1 interaction to 3-O-sulfated heparan sulfate in mouse-derived DRG explant and profiles of inflammatory markers during virus infection
por: Sharthiya, Harsh, et al.
Publicado: (2017)

Free-living and captive turtles and tortoises as carriers of new Chlamydia spp.
por: Mitura, Agata, et al.
Publicado: (2017)

Killing of diverse eye pathogens (Acanthamoeba spp., Fusarium solani, and Chlamydia trachomatis) with alcohols
por: Aqeel, Yousuf, et al.
Publicado: (2017)

Alternative strategies for Chlamydia treatment: Promising non-antibiotic approaches
por: Hou, Chen, et al.
Publicado: (2022)

Outcome of urogenital infection with Chlamydia muridarum in CD-14 gene knockout mice
por: Imtiaz, Muhammad T, et al.
Publicado: (2006)

Understanding Dermatan Sulfate−Heparin Cofactor II Interaction through Virtual Library Screening
por: Raghuraman, Arjun, et al.
Publicado: (2010)

The Contribution of Chlamydia-Specific CD8(+) T Cells to Upper Genital Tract Pathology
por: Vlcek, Kelly R., et al.
Publicado: (2015)

The Chlamydia muridarum plasmid revisited : new insights into growth kinetics
por: Skilton, Rachel J., et al.
Publicado: (2018)

A molecular survey of Chlamydia spp. infection in commercial poultry and detection of Chlamydia pneumoniae in a commercial turkey flock in Iran
por: Hashemian, Seyed Mohammad Mahdi, et al.
Publicado: (2023)

Synthetic biology: promises and challenges
por: Serrano, Luis
Publicado: (2007)

Archaic connectivity between the sulfated heparan sulfate and the herpesviruses – An evolutionary potential for cross-species interactions
por: Elste, James, et al.
Publicado: (2023)

Combinatorial Virtual Library Screening Study of Transforming Growth Factor-β2–Chondroitin Sulfate System
por: Sankaranarayanan, Nehru Viji, et al.
Publicado: (2021)

A Simple Method for Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation of Key Principles from Heparin/Heparan Sulfate-Binding Proteins
por: Sarkar, Aurijit, et al.
Publicado: (2015)

Molecular prevalence and genotyping of Chlamydia spp. in wild birds from South Korea
por: JEONG, Jipseol, et al.
Publicado: (2017)

Detection and identification of Chlamydia spp. from pigeons in Iran by nested PCR and sequencing
por: Golestani, Nadia, et al.
Publicado: (2020)

Frequency of Mycoplasma pneumoniae, Legionella pneumophila and Chlamydia spp. among patients with atypical pneumonia in Tehran
por: Noori Goodarzi, N., et al.
Publicado: (2020)

Discovering small-molecule therapeutics against SARS-CoV-2
por: Tiwari, Vaibhav, et al.
Publicado: (2020)

In-Depth Molecular Dynamics Study of All Possible Chondroitin Sulfate Disaccharides Reveals Key Insight into Structural Heterogeneity and Dynamism
por: Nagarajan, Balaji, et al.
Publicado: (2022)

On the Selectivity of Heparan Sulfate Recognition by SARS-CoV-2 Spike Glycoprotein
por: Chittum, John E., et al.
Publicado: (2021)

Sulfated Galactofucans: An Outstanding Class of Fucoidans with Promising Bioactivities
por: Zayed, Ahmed, et al.
Publicado: (2022)

Inactivation of Salmonella spp. and Listeria spp. by Palmitic, Stearic, and Oleic Acid Sophorolipids and Thiamine Dilauryl Sulfate
por: Zhang, Xuejie, et al.
Publicado: (2016)

Mycoplasma pneumoniae and Chlamydia spp. Infection in Community-Acquired Pneumonia, Germany, 2011–2012
por: Dumke, Roger, et al.
Publicado: (2015)

Chlamydia spp. development is differentially altered by treatment with the LpxC inhibitor LPC-011
por: Cram, Erik D., et al.
Publicado: (2017)

Coinfection of Chlamydia spp. and herpesvirus in juvenile farmed Siamese crocodiles (Crocodylus siamensis) in Thailand
por: Paungpin, Weena, et al.
Publicado: (2021)

Occurrence of Chlamydia spp. in Conjunctival Samples of Stray Cats in Timișoara Municipality, Western Romania
por: Tîrziu, Andreea, et al.
Publicado: (2022)

The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus entry into host cells
por: Mitra, Dipanwita, et al.
Publicado: (2021)

On the Specificity of Heparin/Heparan Sulfate Binding to Proteins. Anion-Binding Sites on Antithrombin and Thrombin Are Fundamentally Different
por: Mosier, Philip D., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_anlaf9cg4tcg9n3cmjk7o22i8n