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Multivalency in Rab effector interactions

Rab proteins regulate vesicular transport in eukaryotic cells and establish connections to various cellular structures and processes by interacting with so-called effector molecules. Several of these effectors are known to not only bind a single Rab protein, but to be able to bind multiple different...

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Detalles Bibliográficos
Autores principales: Rai, Amrita, Goody, Roger S., Müller, Matthias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343607/
https://www.ncbi.nlm.nih.gov/pubmed/28129037
http://dx.doi.org/10.1080/21541248.2016.1265700
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author Rai, Amrita
Goody, Roger S.
Müller, Matthias P.
author_facet Rai, Amrita
Goody, Roger S.
Müller, Matthias P.
author_sort Rai, Amrita
collection PubMed
description Rab proteins regulate vesicular transport in eukaryotic cells and establish connections to various cellular structures and processes by interacting with so-called effector molecules. Several of these effectors are known to not only bind a single Rab protein, but to be able to bind multiple different Rabs simultaneously. In this review we will give a short overview of effectors in general and (putative) functions of the aforementioned multivalent Rab:effector interactions.
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spelling pubmed-63436072019-01-31 Multivalency in Rab effector interactions Rai, Amrita Goody, Roger S. Müller, Matthias P. Small GTPases Mini-Review - Commissioned Rab proteins regulate vesicular transport in eukaryotic cells and establish connections to various cellular structures and processes by interacting with so-called effector molecules. Several of these effectors are known to not only bind a single Rab protein, but to be able to bind multiple different Rabs simultaneously. In this review we will give a short overview of effectors in general and (putative) functions of the aforementioned multivalent Rab:effector interactions. Taylor & Francis 2017-01-27 /pmc/articles/PMC6343607/ /pubmed/28129037 http://dx.doi.org/10.1080/21541248.2016.1265700 Text en © 2016 The Author(s). Published with license by Taylor & Francis. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Mini-Review - Commissioned
Rai, Amrita
Goody, Roger S.
Müller, Matthias P.
Multivalency in Rab effector interactions
title Multivalency in Rab effector interactions
title_full Multivalency in Rab effector interactions
title_fullStr Multivalency in Rab effector interactions
title_full_unstemmed Multivalency in Rab effector interactions
title_short Multivalency in Rab effector interactions
title_sort multivalency in rab effector interactions
topic Mini-Review - Commissioned
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343607/
https://www.ncbi.nlm.nih.gov/pubmed/28129037
http://dx.doi.org/10.1080/21541248.2016.1265700
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