Evolution of a comprehensive, orthogonal approach to sequence variant analysis for biotherapeutics

Amino acid sequence variation in protein therapeutics requires close monitoring during cell line and cell culture process development. A cross-functional team of Pfizer colleagues from the Analytical and Bioprocess Development departments worked closely together for over 6 years to formulate and com...

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Detalles Bibliográficos
Autores principales: Lin, T. Jennifer, Beal, Kathryn M., Brown, Paul W., DeGruttola, Heather S., Ly, Mellisa, Wang, Wenge, Chu, Chia H., Dufield, Robert L., Casperson, Gerald F., Carroll, James A., Friese, Olga V., Figueroa, Bruno, Marzilli, Lisa A., Anderson, Karin, Rouse, Jason C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343769/
https://www.ncbi.nlm.nih.gov/pubmed/30303443
http://dx.doi.org/10.1080/19420862.2018.1531965

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