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Urease is an essential component of the acid response network of Staphylococcus aureus and is required for a persistent murine kidney infection

Staphylococcus aureus causes acute and chronic infections resulting in significant morbidity. Urease, an enzyme that generates NH(3) and CO(2) from urea, is key to pH homeostasis in bacterial pathogens under acidic stress and nitrogen limitation. However, the function of urease in S. aureus niche co...

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Detalles Bibliográficos
Autores principales: Zhou, Chunyi, Bhinderwala, Fatema, Lehman, McKenzie K., Thomas, Vinai C., Chaudhari, Sujata S., Yamada, Kelsey J., Foster, Kirk W., Powers, Robert, Kielian, Tammy, Fey, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343930/
https://www.ncbi.nlm.nih.gov/pubmed/30608981
http://dx.doi.org/10.1371/journal.ppat.1007538